Meckel-Gruber Syndrome is a Fatal congenital autosomal recessive disease which is named after the German anatomist Johann Friedrich Meckel and the German physician Georg Gruber. This illness infects 1 in 13,250 to 1 in 140,000 people around the world; however, it’s more common in some regions. For instance, it was reported that Meckel syndrome has an incidence of 1 per 3,500 live births with a carrier rate of 1 in 30 in Bedouins in Kuwait (Teebi et al.1992). This essay will define Meckel syndrome by introducing its causes, symptoms, and treatment.
The two main causes of Meckel-Gruber syndrome are genetic inheritance and gene mutation. Hereditary diseases are controlled by two genes, one acquired from the