In this phase, the wound is rebuilt with new granulation tissue which consists of extracellular matrix and collagen, and new blood vessels develop. The granulation tissue depends on oxygen and nutrients produced by the blood vessels for a healthy healing process of the wound. The color of the granulation tissue can determine whether or not the wound is infected or healthy (Phases of Wound Healing, par 2). Next the epithelial cells resurface the wound to create a barrier between the wound and the environment. Once epithelialization has occurred and the wound is closed, it moves into the phase known as maturation or remodeling. In maturation or remodeling, the collagen is replaced and the cross fibers are rearranged, linked together and aligned along the tension lines (Wikipedia, Wound
In this phase, the wound is rebuilt with new granulation tissue which consists of extracellular matrix and collagen, and new blood vessels develop. The granulation tissue depends on oxygen and nutrients produced by the blood vessels for a healthy healing process of the wound. The color of the granulation tissue can determine whether or not the wound is infected or healthy (Phases of Wound Healing, par 2). Next the epithelial cells resurface the wound to create a barrier between the wound and the environment. Once epithelialization has occurred and the wound is closed, it moves into the phase known as maturation or remodeling. In maturation or remodeling, the collagen is replaced and the cross fibers are rearranged, linked together and aligned along the tension lines (Wikipedia, Wound