Much like thrombocytopenia, thrombophilia is an inherited gene meaning it is passed down through genes rather than influenced by the environment. The gene mutation that causes the most common types of thrombophilia is called Factor V Leiden. Within the European population, around 5,000 people have two copies of this mutation within their chromosomes making them the most affected. Other populations like the African or Indonesian population are less susceptible to thrombophilia. This is due to the weather as the cold has an effect upon the heart and the way the blood is pumped around the body. For example, in England it is cold most of the year meaning English people have to find methods of keeping themselves warm however, the heart can only pump blood around the body to keep the body warm. If the body is too cold the heart will work harder to pump more blood around the body so the body temperature rises. More blood rushing around the body means more blood cells react with the chemicals and this will alter the blood performance. Alteration of the blood may cause blood clots which ultimately lead to thrombophilia. As mentioned, Europeans are the most susceptible to the Factor V Leiden gene mutation. The blood clots formed due to the Factor V Leiden can be so severe that they can break away from their original position in the body and travel through the blood stream which is extremely dangerous as they could get stuck in the pulmonary artery which is the main artery linked to the lungs. These blood clots within the pulmonary artery are known as pulmonary
Much like thrombocytopenia, thrombophilia is an inherited gene meaning it is passed down through genes rather than influenced by the environment. The gene mutation that causes the most common types of thrombophilia is called Factor V Leiden. Within the European population, around 5,000 people have two copies of this mutation within their chromosomes making them the most affected. Other populations like the African or Indonesian population are less susceptible to thrombophilia. This is due to the weather as the cold has an effect upon the heart and the way the blood is pumped around the body. For example, in England it is cold most of the year meaning English people have to find methods of keeping themselves warm however, the heart can only pump blood around the body to keep the body warm. If the body is too cold the heart will work harder to pump more blood around the body so the body temperature rises. More blood rushing around the body means more blood cells react with the chemicals and this will alter the blood performance. Alteration of the blood may cause blood clots which ultimately lead to thrombophilia. As mentioned, Europeans are the most susceptible to the Factor V Leiden gene mutation. The blood clots formed due to the Factor V Leiden can be so severe that they can break away from their original position in the body and travel through the blood stream which is extremely dangerous as they could get stuck in the pulmonary artery which is the main artery linked to the lungs. These blood clots within the pulmonary artery are known as pulmonary