Neonatal intensive care unit (NICU) are intensive medical care unit for newborn baby who born in low weight, early born and develop problems on birth. It provides critical care for babies less than 1 month and at birth. NICU is a combination of trained health care and advanced technology to provide care for babies. Newborn who admitted in NICU are susceptible to infection especially neonates which has immature host defense mechanisms. In NICU, this neonate frequently expose to antibiotics and invasive procedure environment. Neonates are at higher risk of developing an infection and certain health problem raise baby risk for the infection. Infection occurs when body exposed and germs enter the body. Nosocomial infection usually happen on population of extremely low birth weight (ELBW) as the babies will hospitalized for long period and exposure numerous invasive procedure (Polin & Saiman, 2003). Preterm baby who hospitalized in NICU are babies more susceptible to infection and mortality because of immature immune system (Brady, 2005). Prevention and treatment in NICU is very important on nosocomial infection. World Health Organization (WHO) and Centers …show more content…
difficile when perform sterile procedures and touch areas of hospitalization patient’s skin (Larson, Aiello, & Cimiotti, 2004). Study show overall level of hand hygiene compliance low which cause incidence of infection estimated about 5-10%, direct cause of death 3% of patients, nosocomial infection result of hospitalization longer and increase significant cost (Ali, Zahra, & Khalil, 2016).According to a Canadian study carried by assess 17 NICUs on health associated infection and found 78.7% of very low birth infant develop at least one health associated infection while 16.2% experienced two health associated infection and 5.1% experienced three and more (Aziz, et al.,