The study also looked at the levels of Glu-osteocalcin (Glu-OC) and menaquinone-4 at the end of 24 months period, as well as osteocalcin (OC) level and deoxypyridinoline (DPD) urinary elimination, which were recorded before and after the treatment course. Patients were randomized to two groups. The control group (n= 121) received 150 mg of elemental calcium once a day, and the vitamin K2 group (n=120) was treated with 45 mg per day of oral vitamin K2 and 150 mg of elemental calcium once a day for 24 months. The patients were not allowed to take any other medications that effected bone or calcium metabolism. However, there were no specific instructions provided regarding daily calcium, vitamin D or vitamin K intake. Additionally, no exercise activity instructions were
The study also looked at the levels of Glu-osteocalcin (Glu-OC) and menaquinone-4 at the end of 24 months period, as well as osteocalcin (OC) level and deoxypyridinoline (DPD) urinary elimination, which were recorded before and after the treatment course. Patients were randomized to two groups. The control group (n= 121) received 150 mg of elemental calcium once a day, and the vitamin K2 group (n=120) was treated with 45 mg per day of oral vitamin K2 and 150 mg of elemental calcium once a day for 24 months. The patients were not allowed to take any other medications that effected bone or calcium metabolism. However, there were no specific instructions provided regarding daily calcium, vitamin D or vitamin K intake. Additionally, no exercise activity instructions were