Diagnosis of LP was confirmed based on the typical clinical presentation. Patients were subgrouped into two main groups; patients with only OLP lesions or patients with mainly CLP lesions (generalized, localized or associated with OLP). Patients on phototherapy, or suffering from any cancer, or receiving systemic treatment within the last 4 weeks have been excluded from the study. …show more content…
All subjects signed a written informed consent before enrolment.
Three ml venous blood sample was taken after fasting overnight (12 h) from each subject for detection of MTHFR gene polymorphism by PCR-RFLP technique and for measurement of the following laboratory investigations: plasma cholesterol, triglycerides, high-density lipoprotein (HDL), Presence of hypertension has been assessed. Hcy and folic acid were measured by ELISA kit supplied by (CUSABIO) and (MyBioSource) respectively according to manufacturer’s