The defining characteristic of ALS is the death of the upper and lower motor neurons in the brain, brain stem, and spinal cord of the brain. Prior to their destruction, motor neurons develop protein components in their cellular bodies and axons. These components are often combined with and combining one of the proteins associated with ALS: SOD1, TDP-43, or FUS. These components are non-amyloid aggregates. This disease has been found to contradict plaque and protein accumulation. The TDP-43 protein produced by this genetic anomaly is toxic. Patients with the disease have been found to have abnormal TDP proteins in dying neurons, but it is believed that this structure can be created by damaged cells that attempt to repair themselves. The oxygen uptake system consists of superoxide dismutase enzymes, catalase and glutathione peroxidase. In this collection, SOD is a key enzyme, because it is involved in the first phase of the removal of free radicals. Three ISO-enzymes have been identified, including SOD, cytosolic (Cu / Zn SOD), mitochondrial SOD (Mn-SOD) and extracellular SOD
The defining characteristic of ALS is the death of the upper and lower motor neurons in the brain, brain stem, and spinal cord of the brain. Prior to their destruction, motor neurons develop protein components in their cellular bodies and axons. These components are often combined with and combining one of the proteins associated with ALS: SOD1, TDP-43, or FUS. These components are non-amyloid aggregates. This disease has been found to contradict plaque and protein accumulation. The TDP-43 protein produced by this genetic anomaly is toxic. Patients with the disease have been found to have abnormal TDP proteins in dying neurons, but it is believed that this structure can be created by damaged cells that attempt to repair themselves. The oxygen uptake system consists of superoxide dismutase enzymes, catalase and glutathione peroxidase. In this collection, SOD is a key enzyme, because it is involved in the first phase of the removal of free radicals. Three ISO-enzymes have been identified, including SOD, cytosolic (Cu / Zn SOD), mitochondrial SOD (Mn-SOD) and extracellular SOD