Idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) – the most common form of idiopathic interstitial pneumonia – is a chronic, progressive fibrotic lung disease that affects older adults. IPF is characterized by a continuing decline in lung function, poor survival, and limited therapeutic options. The invasive proliferation of fibrous tissue and scarring of the interstitium lead to a decline in forced vital capacity (FVC) (Richeldi et al. 2014). IPF has a poor prognosis; the median survival for the disease is between 3 and 5 years after diagnosis (Padilla 2015). In the past, inflammation was believed to be the principal feature of IPF and treatment comprised of corticosteroids. As this belief was discarded, the only effective treatment became lung transplantation…

Idiopathic pulmonary fibrosis (IPF) is a progressive chronic interstitial lung disease of unknown origin that carries a potentially fatal prognosis. The course is usually indolent but inevitable 1;2. The disease damages mainly the alveolar epithelial cell, with increased interstitial deposition of extracellular matrix (ECM), and enhanced fibroblast/myofibroblast proliferation. It progresses to loss of respiratory function and distortion of normal lung architecture 1;3. A variety of animal…

Idiopathic Pulmonary Fibrosis is an isolated disease that progresses over time. There is no known direct cause for the disease. IPF affects the lungs and the body getting much needed oxygen. Some symptoms that may develop over time such as shallow breathing, fatigue, and clubbing. There are very few treatments for the disease. Personally, having a family member go through this disease, it is amazing he is still alive today. IPF causes the lungs to become rigid, firm, scarred and over time lose…

Conclusion Idiopathic pulmonary fibrosis is a disease without a known cause or cure, which targets the lungs, causing a progressive decline in respiratory function and overall quality of life. These patients silently suffer, as PROMIS scale scores indicate that depression in these patients are comparable to those in people with major depressive disorder, fatigue that presents slightly worse than those of people with heart failure, sleep disturbances that compare to those with obstructive sleep…

There are a few clinical management steps that can help reduce or delay the effects of Idiopathic Pulmonary Fibrosis signs and symptoms. Shortness of breath is the most pressing and negative symptom of IPF. There is not a permanent fix that can be done; however, oxygen therapy is the best option. Oxygen therapy provides an inflow of oxygen into the lungs through the use of nasal prongs or an oxygen mask (National Institutes of Health, 2011). This can be accomplished using a portable tank for…

Final Paper: Measuring Change in HRQoL of ITP Patients in Japan treated by Eltrombopag Introduction Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder, which is characterized by a low platelet count caused by both increased platelet destruction and insufficient platelet production [1]. In Japan, there are 20,000 patients with ITP and the incidence of ITP is estimated at 3,000 per year [2]. Major signs and symptoms include red spots and/or bruising on the skin, prolonged…

The most common manifestations are pancreatic insufficiency, meconium ileus, distal intestinal obstruction syndrome (DIOS), gastro-oesophageal reflux disease (GORD) and liver disease. Children with cystic fibrosis often suffer from growth failure caused by malabsorption. For this reason, nutritional support is essential to achieve normal growth. Pharmacists can evaluate the use of dietary supplements because they may interact with other prescribed medications (Murray et al., 2008, cited in…

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Cystic Fibrosis is a disease that is life threatening. It is a genetic disease that causes persistent lung infections and progressively limits the ability to breathe. People with CF have a defective gene that causes thick, build up of mucus in the lungs, pancreas, and other organs. The mucus will clog the airways and trap bacteria in the lungs, which causes infections, extensive lung damage, and leads to respiratory failure. The mucus in the pancreas prevents the release of digestive enzymes…