The pharmaceuticals U-50.488H in 0.6 and 1.25 mg/kg doses for control animals was ineffective for behaviour changes. In the same time the 2.5 mg/kg dose decreased the number of approaches compare to the behaviour of animals, which got injected with saline (p < 0.001) and the pharmaceuticals in 0.6 mg/kg dose (p < 0.05) and 1.25 mg/kg (p < 0.001).
For aggressive male mice the pharmaceuticals with 2.5 mg/kg dose decreased the number of approaches to partition compare to behaviour of animals, which got injected with saline (p < 0.01) and the pharmaceuticals in 0.6 mg/kg (p < 0.05) and 1.25 mg/kg (p < 0.01) doses. The general reaction time on the partner significantly did not change under the influence of pharmaceuticals. The average duration in one approach for aggressors was significantly …show more content…
The number (p < 0.05) and the time (p < 0.01) significantly decreased for them in demonstration of autogrooming after the injection of the pharmaceuticals in 2.5-mg/kg dose. The significant differences were found in demonstration time of autogrooming between the effects of 1.25 and 2.5-mg/kg doses p < 0.05).
For submissive animals the latent time of the first run increased under the effect of the pharmaceuticals with 1.25 mg/kg dose (p < 0.05), the number (p < 0.05) and the time (p < 0.01) of demonstration of ramps under the effect of 2.5 mg/kg dose compare to the injection on saline. The significant differences between the effects of 0.6 and 2.5 mg/kg doses were found in the number of crossed squares (p < 0.05), for the number (p < 0.01) and the time (p < 0.01) of ramps. The differences between effects of 1.25 and 2.5 mg/kg doses were found in number of crossed squares (p <
For aggressive male mice the pharmaceuticals with 2.5 mg/kg dose decreased the number of approaches to partition compare to behaviour of animals, which got injected with saline (p < 0.01) and the pharmaceuticals in 0.6 mg/kg (p < 0.05) and 1.25 mg/kg (p < 0.01) doses. The general reaction time on the partner significantly did not change under the influence of pharmaceuticals. The average duration in one approach for aggressors was significantly …show more content…
The number (p < 0.05) and the time (p < 0.01) significantly decreased for them in demonstration of autogrooming after the injection of the pharmaceuticals in 2.5-mg/kg dose. The significant differences were found in demonstration time of autogrooming between the effects of 1.25 and 2.5-mg/kg doses p < 0.05).
For submissive animals the latent time of the first run increased under the effect of the pharmaceuticals with 1.25 mg/kg dose (p < 0.05), the number (p < 0.05) and the time (p < 0.01) of demonstration of ramps under the effect of 2.5 mg/kg dose compare to the injection on saline. The significant differences between the effects of 0.6 and 2.5 mg/kg doses were found in the number of crossed squares (p < 0.05), for the number (p < 0.01) and the time (p < 0.01) of ramps. The differences between effects of 1.25 and 2.5 mg/kg doses were found in number of crossed squares (p <