Professor’s Name
Course Name
Date
Discussion Post
A comparison of how the two patients will metabolize the drug considering weight, gender, distribution of body water and body fat, age, metabolic state, and alcohol use.
From the descriptions of the two patients, Ms. Jones is likely to metabolize orally admitted drugs faster that Mr. Smith. The more on is older one is, the slower a drug will be absorbed by the body. Since drugs depend on the amount of gastric fluid in a patient’s body, Mr. Smith’s body would metabolize the drugs slowly due to the little amount of gastric juice he possesses. When it comes to body weight, Ms. Jones body is likely to absorb the drugs faster than Mr. Smith. The absorption of drugs highly depends on the surface it has to cover in a patient’s body (Gunja 157). …show more content…
Therefore, Ms. Jones and Mr. Smith bodies will absorb drugs the same way if all other factors remain constant. The frequency of drinking alcohol also affects the rate at which drugs will be metabolized in a Patient’s body. Therefore, Ms. Jones is likely to metabolize drugs slower than Mr. Smith.
An explanation of how these factors impact the pharmacokinetics of the drug (half-life, dosage, route of administration, and elimination of the drug)
The above-discussed factors highly determine the pharmacokinetics of the drugs to a patient. For instance, the age of an individual patient will determine the dosage one is given by the doctor. The metabolic rate of an old person is normally low, thus, needs a higher dosage of drugs (Roehrs and Roth 729). Therefore, Mr. Smith is likely to be given a higher dosage and use of direct injection as the administration method.
Evaluation of the impact on the risk-benefits analysis of the use of the