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67 Cards in this Set
- Front
- Back
Associated Neoplasm: Down Syndrome
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ALL, AML
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Associated Neoplasm: Xeroderma pegmetosum, albinism
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Melanoma, basal cell carcinoma, and especially squamous cell carcinoma
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Associated Neoplasm: Chronic atrophic gastritis, pernicious anemia
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Gastric Adenocarcinoma
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Associated Neoplasm: Tuberous sclerosis (facial angiofibroma, seizures, mental retardation)
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Astrocytoma, Angiomyolipoma, and cardiac rhabdomyoma
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Associated Neoplasm: Actinic keratosis
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Squamous Cell Carcinoma of skin
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Associated Neoplasm: Barrett's Esophagus
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Esophageal Adenocarcinoma
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Associated Neoplasm: Plummer-Vinson Syndrome (atrophic glossitis, esophageal webs, anemia; all due to Fe def)
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Squamous Cell Carcinoma of esophagus
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Associated Neoplasm: Cirrhosis
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Hepatocellular Carcinoma
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Associated Neoplasm: Ulcerative Colitis
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Colonic Adenocarcinoma
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Associated Neoplasm: Paget's disease of the bone
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Secondary osteosarcoma
Fibrosarcoma |
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Associated Neoplasm: Immunodeficiency States
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Malignant Lymphomas
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Associated Neoplasm: AIDS
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Aggressive Malignant Lymphoma
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Associated Neoplasm: Autoimmune disease
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Benign and Malignant Lymphomas
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Associated Neoplasm: Acanthosis Nigricans
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Visceral Malignancy
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Associated Neoplasm: Dysplastic Nevus
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Malignant Melanoma
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Associated Neoplasm: Radiation Exposure
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Sarcoma
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Associated Tumor: abl
Oncogene or Tumor suppressor? |
CML
oncogene |
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Associated Tumor: c-myc
Oncogene or Tumor suppressor? |
Burkitt's lymphoma
Oncogene |
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Associated Tumor: bcl-2
Oncogene or Tumor suppressor? |
Follicular and undifferentiated lymphoma
Oncogene |
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Associated Tumor: erb-B2
Oncogene or Tumor suppressor? |
Breast, ovarian, and gastric carcinoma
Oncogene |
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Associated Tumor: ras
Oncogene or Tumor suppressor? |
colon carcinoma
Oncogene |
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Associated Tumor: L-myc
Oncogene or Tumor suppressor? |
Lung Cancer
Oncogene |
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Associated Tumor: N-myc
Oncogene or Tumor suppressor? |
Neuroblastoma
Oncogene |
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Associated Tumor: ret
Oncogene or Tumor suppressor? |
MEN II and III
Oncogene |
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Associated Tumor: c-kit
Oncogene or Tumor suppressor? |
Gastrointestinal stromal tumor
Oncogene |
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Associated Tumor: Rb
Oncogene or Tumor Suppressor |
Retinoblastoma, Osteosarcoma
Tumor Suppressor |
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Associated Tumor: BRCA1
Oncogene or Tumor Suppressor |
Breast and Ovarian Cancer
Tumor Suppressor |
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Associated Tumor: BRCA2
Oncogene or Tumor Suppressor |
Breast
Tumor Suppressor |
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Associated Tumor: p53
Oncogene or Tumor Suppressor |
Most cancers
Tumor Suppressor |
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Associated Tumor: p16
Oncogene or Tumor Suppressor |
Melonoma
Tumor Suppressor |
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Associated Tumor: APC
Oncogene or Tumor Suppressor |
Colorectal Cancer (FAP)
Tumor Suppressor |
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Associated Tumor: WT1
Oncogene or Tumor Suppressor |
Wilm's Tumor
Tumor Suppressor |
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Associated Tumor: NF1
Oncogene or Tumor Suppressor |
Neurofibromatosis Type 1
Tumor Suppressor |
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Associated Tumor: NF2
Oncogene or Tumor Suppressor |
Neurofibromatosis Type 2
Tumor Suppressor |
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Associated Tumor: DPC
Oncogene or Tumor Suppressor |
Pancreatic Cancer
Tumor Suppressor |
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Associated Tumor: DCC
Oncogene or Tumor Suppressor |
Colon Cancer
Tumor Suppressor |
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Name the Neoplasm: Patient with Cushing's syndrome
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ACTH - Small Cell Lung Cancer
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Name the Neoplasm: Patient with SIADH
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ADH - Small Cell Lung Cancer and Intracranial neoplasms
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Name the Neoplasm: Patient with Hypercalcemia
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PTH - Squamous Cell Lung Carcinoma, renal cell carcinoma, and Breast Cancer
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Name the Neoplasm: Patient with Polycethemia
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EPO - Renal Cell Carcinoma, hemangioblastoma
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Name the Neoplasm: Patient with Lambert-Eaton Syndrome (progressive weakness w/out facial involvement)
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Antibodies against presynaptic Ca2+ channels and NMJ - Thymoma, Small Cell Lung Cancer
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Name the Neoplasm: Patient with Gout and/or urate nephropathy
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Excessive Nucleic Acids - Leukemias and lymphomas
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Psammoma bodies are found in these 4 cancers:
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1. Papillary adenocarcinoma of the thyroid
2. Serous papillary cystadenocarcinoma of ovary 3. Meningioma 4. Malignant mesothelioma PSaMMoma |
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Associated pathology(s): PSA
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Prostate-specific antigen -
Prostate carcinoma BPH Prostatitis |
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Associated pathology(s): Prostatic acid phosphatase
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Prostate carcinoma
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Associated pathology(s): CEA
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Carcinoembryonic antigen - very nonspecific. + in ~70% of colorectal and pancreatic cancers. Also in breast and gastric tumors
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Associated pathology(s): a-Fetoprotein
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NTDs
Hepatocellular carcinoma Nonseminomatous germ cell tumor (yolk sac tumor) DECREASED in Downs Syndrome |
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Associated pathology(s): BhCG
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Hydatidiform moles
Choriocarcinomas Gestational trophoblastic tumors |
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Associated pathology(s): CA-125
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Ovarian Cancer
Malignant epithelial tumors |
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Associated pathology(s): S-100
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Melanoma
Neural tumors Astrocytoma |
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Associated pathology(s): Alkaline phosphatase
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Bone Metastases
Obstructive biliary Disease Paget's disease |
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Associated pathology(s): Bombesin
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Neuroblastoma
Lung and Gastric Cancer |
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Associated pathology(s): TRAP
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Tartrate-resistant acid phophatase.
Hairy cell leukemia |
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Associated pathology(s): CA-19-9
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Pancreatic adenocarcinoma
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Affected Enzyme in Pb poisoning
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Ferrochelatase and ALA dehydratase
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Affected Enzyme in acute intermittent porphyria
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Uroporphyrinogen I Synthase
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Affected Enzyme in Porphyria cutanea tarda
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Uroporphyrinogen decarboxylase
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Accumulated substrate in Pb poisoning
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Coproporphyrin and ALA
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Accumulated substrate in acute intermittent porphyria
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Porphobilinogen and delta-ALA
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Accumulated substrate in Porphyria cutanea tarda
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Uropophyrin
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t(9,22)
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Philadelphia chromsome - CML (bcr-abl hybrid)
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t(8,14)
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Burkitt's lymphoma (c-myc)
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t(14,18)
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Follicular lymphomas (bcl-2)
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t(15,17)
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M3 type of AML (responsive to all-trans retinoic acid)
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t(11,22)
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Ewing's sarcoma
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t(11,14)
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Mantle cell lymphoma
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t(8,21)
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M2 of AML
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