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15 Cards in this Set

  • Front
  • Back

What is used as a marker for GFR?



Why?

serum Creatinine (SCr)


(normal range btwn 0.6-1.2 mg/dL)



Bc its not reabsorbed, secreted, or synthesized

What does CKD depend on?

age


sex


muscle mass


race


prior value

If SCr doubles how does kidney function change?

kidney function is decreased 50%



(1/SCr = Kidney fxn)

What is a better indicator of kidney function then creatinine?


Why is it not as commonly used?

Cystatin C



expensive

Chronic Kidney Disease (CKD) is classified using what?

GFR & albuminuria

Chronic Kidney Disease (CKD) risk factors

Hypertension


Diabetes


Age > 60


Family Hx


Nephrotoxic Drug exposure


CVD


Acute renal failure


Urologic disorers


Systemic Infection


Cancer


Ethnic minority

Indicators of CKD

Proteinuria, Hematuria, or other urine abnorm.


Imaging abnorm.


GFR < 60 mL/min

MC sx of CKD

NONE



(usually do not have sx, must monitor at risk patients!)

CKD common sy/sx

fatigue


easy bruising


metallic taste


urinous breath


hypertension


nocturia


isothenuria


lost libido / impotence


peripheral neuropathy

T/F


Patients w CKD are more likely to die then to progress to ESRD

TRUE



(after CKD diagnosis, pts will eventually progress to ESRD or die, but usually die first, high mortality)

Complications associated w/ CKD

anemia


HTN


CVD


DM


Osteodystrophy


Malnutrition


Metabolic Acidosis


Dyslipidemia

What is the goal of CKD treatment?

extend life expectancy

CKD: TX

Manage:


BP: ACE/ARB


DM: monitor blood glucose
Acidosis: Sodium Bicarb or Citrate


Uric acid: Allopurinol


Secondary Hyperparathyroidism: Low Phosphate diet, Phosphate binders, Ca2+, Vit D analogs



Dialysis


Kidney Transplant

When should a CKD pt start dialysis?

when CKD begins to progress to ESRD

When should a CKD pt be sent to the nephrologist?


CKD 3 or higher