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20 Cards in this Set
- Front
- Back
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Antibiotics |
Chemicals produced naturally by some fungi and bacteria |
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Natural antibiotics |
Made in nature, inhibits growth of other microorganisms |
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Semi-synthetic antibiotics |
Keeping the active moiety intact by modifying the R group: amoxicillin |
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Synthetic antibiotics |
Produced in labs: sulfonamides |
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Bacteriocidal vs bacteriostatic |
Killing vs inhibiting organism |
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Transmitted |
How much light gets through that measures growth |
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What fixes thymine dimers |
SOS system (fixes pyrimidines) |
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Cell wall synthesis |
PCN, ribosome, cellular components |
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Enzymatic inhibitions |
Inhibit DNA and RNA synthesis |
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Sensitivity test name |
Kirby Bauer antimicrobic sensitivity test |
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To be sensitive is |
If a bacterium is susceptible to the effects of an antibiotic |
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To be resistant is |
If the bacterium is resistant to the effects of antibiotics |
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Intermediate effect |
Means bacteria are gaining resistance and the drug must be used in a higher concentration |
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To qualify in vitro |
We use the Kirby Baur method |
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Agar used in the test |
Mueller-Hinton II agar, pH 7.2-7.4 |
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To determine susceptibility |
Measure the diameter of the zone of inhibition in mm |
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Zone of inhibition |
Area of no growth around antibiotic disk |
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Barriers to prevent UV damage |
Time of exposure, distance, endospores |
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We measure absorbance with |
A spectrophotometer |
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The reading of a spectrophotometer is |
The optical density |
