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99 Cards in this Set

  • Front
  • Back
What makes up the lymphatic system?
Lymph
Lymphatic vessels
Lymphoid tisues
What is the function of the lymph system?
To return fluid to the circulatory system from the intercellular tissue spaces.
What are lymphatic vessels?
Thin walled tubes distributed throughout the body. Particularly numerous in dermis.
What are lymphatic cappillaries?
Network of microscopic lymph tubes. Have a lining of endothelium like blood capillaries. Are more permkeable and drain interstitial fluid.
What is lymph?
Interstitial fluid drained from lymph capillaries.
What are lymphatic vessels?
Larger holding vessels for lymph fluid.
What is the thoracic duct?
The largest lymphatic vessel of the body. Arises in abdominal cavity, between thorax and vertebrae.
Where does the thoracic duct empty?
Left subclavian vein, then jugular vein.
(Fluid goes back to cardiovascular system.)
What does the thoracic duct drain?
Entire body below the diaphragm
Left half of the body above the diaphragm.
What is the right lymphatic duct?
Large lymph vessel.
Drains the right side of body above the diaphragm.
Does the lymphatic system flow in more than one direction?
No.
What are lymph nodes?
Masses of tissue enclosed in capsules.
Occur along pathway of the larger lymphatic velssels. Serve as filters for lymph.
What cells are found in lymph nodes?
T-lymphocytes
B-lymphocytes
What are vessels entering the lymph nodes called?
Afferent lymphatic vessels
What are vessels leaving the lymph nodes?
Efferent lymphatic vessels
What supports the main cells of the lymph nodes, and B- and T-lymphocytes?
Reticular fibers
What are spaces within the lymph nodes called?
Lymph sinuses. - Have relatively few cells.
What is the central region of the lymph node, containing fewer lymphocytes?
Medulla
What do lymphatic vessels do?
Carry lymph from peripheral tissues to veins of the cardiovascular system.
What do lymph nodes do?
Monitor composition of lymph; site of cells that engulf pathogens; immune response
What does the spleen do?
Monitors circulating blood; site of cells that engulf pathogens; site of cells that regulate immune response.
What does the thymus do?
Controls the development and maintenance of T-lymphocytes.
What do tonsils do?
Aggregates of lymph node tissue located under the epithelial lining of the oral and pharyngeal cavities
What are palatine tonsils?
What we normally refer to as "tonsils." Located at the surface of the palatine bone.
What are the pharyngeal tonsils
At the roof of the pharynx, also called adenoids.
What are the lingual tonsils?
Found in the tongue.
Where else are nodules of lymphoid tissue found?
In the wall of the intestinal tract, particularly the ileum.

These are called Peyers Patches.
What is the function of the thymus?
Divided into a number of lobules containing supportive cells and T-lymphocytes.

Produces thymocin, which mature T-lymphocytes.
What does the spleen do?
It is a resevoir of lymphocytes for the body
Filters blood
Macrophages in spleen eat broken red blood cells and send iron to liver.
Storage depot for blood
Contains B and T lymphocytes.
What is the hillus?
The area where large blood vessels enter and leave the spleen.
What supports the main cells of the lymph nodes, and B- and T-lymphocytes?
Reticular fibers
What are spaces within the lymph nodes called?
Lymph sinuses. - Have relatively few cells.
What is the central region of the lymph node, containing fewer lymphocytes?
Medulla
What do lymphatic vessels do?
Carry lymph from peripheral tissues to veins of the cardiovascular system.
What do lymph nodes do?
Monitor composition of lymph; site of cells that engulf pathogens; immune response
What does the spleen do?
Monitors circulating blood; site of cells that engulf pathogens; site of cells that regulate immune response.
What does the thymus do?
Controls the development and maintenance of T-lymphocytes.
What do tonsils do?
Aggregates of lymph node tissue located under the epithelial lining of the oral and pharyngeal cavities
What are palatine tonsils?
What we normally refer to as "tonsils." Located at the surface of the palatine bone.
What are the pharyngeal tonsils
At the roof of the pharynx, also called adenoids.
What are the lingual tonsils?
Found in the tongue.
Where else are nodules of lymphoid tissue found?
In the wall of the intestinal tract, particularly the ileum.

These are called Peyers Patches.
What is the function of the thymus?
Divided into a number of lobules containing supportive cells and T-lymphocytes.

Produces thymocin, which mature T-lymphocytes.
What does the spleen do?
It is a resevoir of lymphocytes for the body
Filters blood
Macrophages in spleen eat broken red blood cells and send iron to liver.
Storage depot for blood
Contains B and T lymphocytes.
What is the hillus?
The area where large blood vessels enter and leave the spleen.
Antibody IgG
Most associated with disease resistance.

Two long chains and two small chains of amino acids (polypeptides.)

Has a hinge where chains diverge, depicted as a Y figure. One end of the molecule is specific for the antigen that elicited its production.
Will interact with that antigen only.

Immune system has capacity to produce a million different kinds of antibodies, one for each different possible antigen.

Antibodies chemically combine with antigen to neutralize microorganism
Antibody IgM
Also involved in resistance

Consists of 20 peptide chains.
First antibody to appear in circulation after infection takes place.
Antibody IgA
8 polypeptide chains.

Interacts with microorganisms at the body surface, and along the respiratory, gastrointestinal and other tracts open to the environment
Antibody IgD
Receptor site on B-lymphocytes for stimulating activation.
Antibody IgE
Produced during allergic reactions.

Fixes itself to basophils and mast cells.

Encourages release of histamine, seratonin, etc. Induce smooth muscle contractions, cause labored breathing, abdominal cramps, hives, etc.
The lymphatic system arises in the tissues and extends toward the
Heart
The lining of the lymphatic capillaries, like that of the blood capillaries, consists of
Endothelium
The largest lymphatic vessel of the body is the
Thoracic duct
The thoracic duct empties its contents into a vein known as the
Subclavian vein
The thoracic duct drains the left side of the head and chest and the entire body below the
Diaphragm
The valves of the lymphatic system operate in a manner similar to the valves of the
Veins
Lymph is filtered in masses of tissue known as
Lymph nodes
The two major types of cells in the lymph nodes are the T-lymphocytes and the
B-lymphocytes
Lymph vessels entering the lymph nodes are referred to as
afferent lymphatic vessels
Extensions of the lymph node capsule pass into the lymph node and separate it into smaller
Lobules
The main cells of the lymph nodes are supported by a series of
Reticular fibers
The cells of the lymph nodes are arranged densely within the outer portion of the lymph node called the
Cortex
At the center of the lymph node, the region is known as the
Cortex
In the process of immunity, the lymph nodes serve as the sites for production of
immune cells
In the neck tissues, the lymph nodes are known as
Cervical lymph nodes
Those lymph nodes located in the armpit are called
Axillary lymph nodes
Lymph nodes may be found in the popliteal fossa, which is located behind the
Knee
Aggregates of lymph node tissue located behind the epithelial lining of the oral cavity are called
Tonsils
One of the important tonsils is located at the surface of a bone known as the
Palatine bone
Primitive cells are modified to form T-lymphocytes in an organ called
Thymus
The thymus is located in the body cavity of the
Thorax
The thymus is relativity large during the development of the
Fetus
The spleen is located in the
Abdominal cavity
The area where large blood vessels enter and leave the spleen is known as the
Hilus
Blood entering the spleen does so by way of the
Splenic artery
The spleen is the organ in the body where destruction occurs in
Red blood cells
Lymph consists of fluid derived from
Interstitial fluid
Lymph sometimes has a milky consistency due to the presence of
fata
Lymph vessels lining the wall of the ileum and jejunum are known as
Lacteals
An accumulation of tissue fluid in the spaces between cells is called
edema
Development of the immune system begins about the third month after
Conception
B-lymphocytes are so named because they are formed in he embryonic chick in an organ called the bursa of
Fabricus
During formation, B-lymphocytes position on their cell membranes a number of receptor sites consisting of
Antibodies
Those substances capable of stimulating the immune system are known as
Antigens
Normally a person's own proteins and polysaccharides do not stimulate the immune system because they are interpreted as
Self
Antigens may enter the bloodstream when they penetrate the skim from a bite by an
Anthropod
The immune system reaches maturity several weeks after a person's
birth
To initiate the immune process, foreign organisms are engulfed by macrophages in the process of
Phagocytosis
The T-lymphocyte the participates in both major immune processes is the
Helper T-lymphocytes
The immune process in which a direct interaction between body cells and microorganisms takes place is the
Cell-mediated immunity
The lymph contains substances unable to pass into capillaries such as
proteins
The T-lymphocyte that exerts a direct interaction with infected body cells is the
cytotoxic T-lymphocyte
Substances secreted by T-lymphocytes that attract macrophages to an infection site are called
lymphokines
T-lymphocytes that prevent the immune process freom becoming overactive are called
suppressor T-lymphocytes
Antibodies are produced by cells derived from B-lymphocytes and known as
plasma cells
The macromolecule composing antibody molecules is
Protein
What are the 5 types of antibodies?
IgA
IgE
IgM
IgD
IgG
The reaction between the antibody molecule and the antigen molecule is said to be highly
specific
Because the polypeptide chains of the antibody molecule diverge, the molecule is often depicted in the shape of the leter
Y