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7 Cards in this Set
- Front
- Back
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enzyme-substrate-complex and product
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-formed when enzyme and substrate interact -once formation of enzyme - substrate complex is complete the substrate molecule undergoes a chemical reaction and is converted to a new product |
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amount of substrate or enzyme present
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concentration of substrate increases, increasing the reaction rate until the enzyme becomes saturated with substrate, where the reaction rate will platue
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coenzymes
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essential for particular enzymes activity, usually donate electrons or protons, most are derived from vitamins
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cofactors
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metallic cations that some enzymes require in order to catalyse a reaction, most are derived from vitamins
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metabolic pathways
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a series of chemical reactions occurring within a cell, these reactions are catalyzed by enzymes, where the product of one enzyme acts as the substrate for the next.
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end product inhibition
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if there is an excess of the end product in a metabolic pathway, the whole pathway is switched off and intermediates do not build up
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rational drug design
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the active site of a molecule is determined ad a second molecule (drug) is constructed to fit into that active site to inhibit the activity of the first molecule
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