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41 Cards in this Set
- Front
- Back
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Thiamine Coenzyme
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Thiamine Pyrophosphate (TPP)
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B2 - Coenzyme
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FAD/FADH2;
FMNFMNH2 |
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Xanthine oxidase
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In liver, MAO deactivates tyramine (toxic amine). MAO inhibitors treat depression and PD. Avoid cheese, beer, wine (high in tyramine).
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Thiamine: a/k/a
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B1
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Riboflavin
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B2
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Nicotinic Acid / Niacin aka
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B3
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Pantothenic Acid
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B5
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Pyridoxine
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B6
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Thiamine- name the Coenzyme
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Thiamine Pyrophosphate (TPP)
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Riboflavin - name the Coenzyme
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FAD/FADH2; FMA/FMNH2
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Nicotinic Acid / Niacin- name the Coenzyme
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NAD+/NADH; NADP+/NADPH
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Pantothenic Acid - name the Coenzyme
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Coenzyme A (CoASH)
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Pyridoxine - name the Coenzyme
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Prydoxal-5'- phosphate (PLP)
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Thiamine- name the Reaction Type
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Decarboxylation, Aldehyde transfer
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Riboflavin -
name the reaction type |
Oxidation/Reduction
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Nicotinic Acid / Niacin- name the Reaction Type
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Oxidatn/Reductn
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Pantothenic Acid - name the Reaction Type
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Acyl transfer
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Pyridoxine - name the Reaction Type
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Removal & replacement of groups from the a-carbon of a.a.'s.
Amino acid: racemases, decarboxylation, transamination |
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Thiamine- name some Example reactions
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--Pyruvate DH, --?-ketoglutarate DH, pyrruvate DC
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Riboflavin - name some Example reactions
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Succinate DH, Monoamine Oxidase, Xanthine Oxidase
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Nicotinic Acid / Niacin- name some Example reactions
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Alcohol metabolism; Lactate DH
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Pantothenic Acid - name some Example reactions
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Transfer of acetyl (2-carbon or more) acyl groups like:
Acetyl CoA; Succinyl CoA |
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Pyridoxine - name some Example reactions
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Alanine racemase, Histidine DC, Alanine, a-ketoglutarate transaminase
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Krebs mnemonic - compounds
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Citrate
Is (isocitrate) a (a-ketoglutarate) sour (succinyl-CoA) substance (succinate) for (fumarate) most (malate) organizisms (oxaloacetate) |
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Amadori rearrangement product
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R-CO--CH2-NH-Protein
glycosylated protein via shiff base reaction |
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Glycolysis mnemonic
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Goodness (Glucose)
Gracious, (Glucose-6-P) Father (Fructose-6-P) Franklin (Fructose-1,6-diP) Did (Dihydroxyacetone-P) Go (Glyceraldehyde-P) By (1,3-Biphosphoglycerate) Picking (3-phosphoglycerate) Pumpkins (2-phosphoglycerate) (to "2") PrEPare (Phosphoenolpyruvate [PEP]) Pies (Pyruvate) |
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Glycolysis enzyme mnemonic
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Hungry - HX/GK
Peter - ph-iso Pan - phosphofructokinase And - aldolase The - triosephosiso Growling - G3P de-H Pink - PG kinase Panther - PG mutase Eat - enolase Pies - pyruvate kinase |
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Aldolase cleaves glucose where?
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in the middle, plucks h from
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Importance of lactate for continuation of glycolysis
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converts NADH back to NAD+ needed for glyceraldehyde 3-phosphate dehydrogenase reaction
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Energy reactions in Krebs (4+1)
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reduce a lot of coenzymes that have to be reoxidzed to continue;
isocitrate deHy gives NADH a-Ketogluatarate deH gives NADH succinate deH gives FADH malate deH gives NADH (also get subs-lvl phos with succ-CoA synthetase) |
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Reactions that need FAD
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Succinate deH
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Reactions that need NAD+
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iso-cit deH; a-ketoglu deH; malate deH; glyceraldehyde-3-phos deH;
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Reactions that need NADH
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Lactate dehydrogenase to form lactate
when yeast convert pyruvate to ethanol |
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Reactions that need ATP
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HX/GK; phosphofructo-kinase;
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Reactions that need ADP
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pyruvate kinase, pholphoglycerate kinase
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Aldolase reacts where?
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pulls the H off the OH at Carbon 4; C3-4 bond breaks and forms alkene at C3-2 but last step ketone forms at C2
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Reactions where Pi is added
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Glyceraldehyde 3-phosphate deH (to 1,3-BPG)
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G3P deH mech
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Differentiate FAD/FMN and NAD+
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FAD/FMN bind tight to enzymes (covalent) while NAD+ binds loose
FAD/FMN can transfer 1e- or 2; NAD+ is 2e- shift (hydride); FADH2/FMNH2 are readily oxidized in air |
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Cysteine protease intemediate
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acyl
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Cystiene protease residues in active site
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CYS, HIS
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