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15 Cards in this Set
- Front
- Back
percentage of the drug dosage that is absorbed
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bioavailability
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entrance of a drug into the bloodstream from its site of administration
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drug absorption
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condition of reliance on the use of a particular drug, characteerized as physical and/or psyc\hological dependence.
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drug dependence
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group of enzymes located primarily in the liver that function to metabolize (biotransformation) drugs.
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drug microsomal metabolizing system (DMMS)
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decreased drug effect occuring after repeated drug administration.
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drug tolerance
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increase in the amount of drug-metabolizing enzymes after repeated administration of certain drugs.
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enzyme induction
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inhibition of drug-metabolizing enzymes by certain drugs
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enzyme inhibition
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drug metabolism that occurs following oral absorption from the GI tract.
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firt-pass metabolism
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time required for the body to rid itself of half of the drug dosage that was absorbed (percent bioavailability)
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half-life
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difference in the effects of drugs and drug dosages from one person to another.
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individual variation
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route of drug administration; drug is injected into gluteal or deltoid muscles.
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intramuscular (IM) injection
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initial drug dose administered to rapidly achieve therapeutic drug concentrations.
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loading dose
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dose administered to maintain drug blood levels in the therapeutic range.
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maintenance dose
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rout of drug administration by way of the mouth through swallowing.
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oral administration
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rout of drug administration that does not involve the gastrointestinal (GI) tract.
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parenteral administration
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