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20 Cards in this Set
- Front
- Back
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Discovered human blood groups in 1901 Found that mixing blood from two individuals can lead to blood clumping |
Austrian Karl Landsteiner |
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Blood clumping is --- which occurs when the receiver of blood transfusion has antibodies against donor blood cell |
Immunological reaction |
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He won --- in --- |
Nobel Prize;1930 |
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Contain haemoglobin, protein thay binds oxygen. RBCs transport oxygen to, and remove carbon dioxide from tissues |
RBC (red blood cell) |
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Fights infection |
WBC (white9 |
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Helps the blood to clot |
Platelets |
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Contains salt and various kinds of proteins |
Plasma |
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Most important used for blood transfusion |
AB0 and Rhesus (Rh) |
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You have A antigens on the surface of RBCs and B antibodies in your blood plasma |
Blood group A |
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You have B antigens on surface of RBC and A antibodies in blood plasma |
Blood group B |
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Both A & B antigens on surface of RBCs, No A and B on blood plasma |
Blood Group AB |
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Neither A or B antigens on RBC, both have A and B antibodies in blood plasma |
Blood group O |
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ABO gene is --- |
Autosomal |
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ABO gene locus is located on --- |
Chromosome 9 |
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A & B blood groups are --- over - |
Dominant over O |
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A & B group genes are --- |
Co dominant |
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Direct detection of ABO antigens Main method used in blood transfusion centres and hospital blood banks |
Serology |
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Serology involves 2 components |
Antibodies that are specific at detecting a particular ABO antigen on RBCs Cells that are of a known ABO group that are agglutinated by the naturally occuring antibodies |
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People with blood group O are called |
Universal donors |
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People with blood group AB are called |
Universal receivers |
