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34 Cards in this Set

  • Front
  • Back

What percent of hormones are proteins?

90

2 categories of non steroid hormones and give examples of each.

1. Peptides/ protein from amino acid


- insulin, glucagon, all pituitary and hypothalamus hormones



2. Amine


- thyroid hormones, catecholamines (epi and noepi), melatonin

Types of steroid hormones

Aldosterone


Cortisol


Estrogen


Testosterone


Progesterone


Vitamin D

These hormones bind to a receptor on the surface of a cell membrane to activate a second messenger within the cell.

Non steroid hormones

Only 2 non steroid hormones that don't need a second messenger.

Insulin and growth hormone

Steroid hormones use what to cause protein synthesis?

Direct gene activation

2nd messenger for adenylyl cyclase mechanism

cAMP

2nd messenger for Phospholipase C mechanism

IP3/Ca2+

2nd messenger for tyrosine kinase mechanism

Insulin and growth hormone

Membrane bound proteins that couple hormone receptors to effector enzymes

G proteins

3 subunits of a g protein

Alpha beta and gamma

When GDP is bound to the alpha subunit, the g protein is ____.

Inactive

Four factors that determine hormone levels

Rate of secretion of hormone from endocrine gland


Rate of metabolism or excretion of hormone


Quantity of transport protein


Changes in plasma volume

3 factors that stimulate endocrine gland activity

Humoral, hormonal, neural

Steroid hormones are ___ soluble and most are formed from ____.

Lipid


Cholesterol

Non steroid hormones are formed from ____.

Proteins and amino acids

Which type of hormone alters activity of dna to modify protein synthesis?

Steroid

What type of connection does the anterior pituitary have and what's it's role in hormones?

Vascular connection


Makes its own hormones

What connection does the posterior pituitary have and what is its role with hormones?

Neural


Store the hypothalamic hormones

2 hormones that are released by hypothalamus and stored in posterior pituitary.

Vasopressin (ADH) and oxytocin

7 hormones released on hypothalamus that activate anterior pituitary

PRH


PIH (DOPAMINE)


TRH


CRH


GHRH


GHIH


GnRH

6 hormones released in anterior pituitary

Prolactin


TSH


ACTH


GH


FSH


LH

3 types of growth by growth hormone

Hyperplasia: cell numbers increase


Production of extracellular matrix: neurons swell


Hypertrophy: cells enlarge

Growth hormone has the opposing effect of the actin of what?

Insulin

Thyroid gland produced mostly which thyroid hormone and which one is more active?

T4


T3

T4 and T3 are transported in the blood bound to carrier proteins called ____.

Thyroxin binding globulin

Primary function of t3 and t4

Heat production

Adrenal medulla is part of which nervous system?

Sympathetic

The adrenal gland is split into what 2 parts?

Adrenal medulla and cortex

The adrenal medulla contains which hormones?

Catecholamines

The adrenal cortex contains which hormones?

Aldosterone


Cortisol


Sex steroid hormones

The only neuron or nerve to go directly to the adrenal medulla

Pre-ganglionic sympathetic neuron

2 major functions of aldosterone

Increase k+ excretion


Increase Na+ and water reabsorption

4 reasons we lower the use of fat % with increasing exercise

Elevated H+ concentration (inhibits HSL)


High levels of lactic acid


Inadequate blood flow to adipose tissue


Insufficient albumin to transport FFA in plasma