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31 Cards in this Set
- Front
- Back
Oxidoreductases |
oxidation-reduction reaction |
|
Transferases |
transfer of a group otherthan hydrogen from one substrate to another |
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Hydrolases |
hydrolysis of various bonds |
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Lyases |
removal of groupsfrom substrates without hydrolysis; product contains double bonds |
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Isomerases |
interconversion ofgeometric, optical, or positional isomers |
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Ligases |
joining of twosubstrate molecules, coupled with breaking of pyrophosphate bond in ATP |
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Activation energy |
energy required to raiseall molecules in 1 mole of a compound at certain temperature to transitionstate at peak of energy barrier |
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Enzymes catalyze reactions by lowering the _________________. |
activation energy |
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In first-order kinetics, reaction rate is: |
directlyproportional to substrate concentration |
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In zero-order kinetics, reaction rate: |
depends only on enzymeconcentration |
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Enzymes are expressed in what units? |
IU/L |
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Creatine Kinase is used to diagnose |
AMI, muscular dystrophy |
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CK-MM is specific to: |
skeletal muscle |
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CK-MB is specific to: |
heart |
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CK-BB is specific to: |
brain |
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Lactate Dehydrogenaseis used to diagnose:
|
pernicious anemia, hemolytic disorders |
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The Lactate Dehydrogenase isoenzyme most abundant in healthy individuals is: |
LD-2 |
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In cardiac necrosis, which Lactate Dehydrogenase isoenzyme concentration exceeds that of LD-2? |
LD-1 |
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AST is used in the diagnosis of: |
hepatocellular and skeletal muscle disorders, |
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The AST assay is based on the: |
Karmen method |
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The tissue source for ALT is: |
liver |
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ALT is used in the diagnosis of: |
hepatic disorders |
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ALP is used in the diagnosis of: |
hepatobiliary and bone disorders |
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ACP is used in the: |
forensic investigation of rape |
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GGT is used in the diagnosis of: |
hepatobiliary disorders, alcoholism |
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Amylase is used in the diagnosis of: |
acute pancreatitis |
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The tissue source for amylase is: |
pancreas and salivary glands |
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The tissue source for lipase is: |
pancreas |
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Lipase is used in the diagnosis of: |
pancreatitis, cholecystitis |
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The tissue source of Glucose-6-PhosphateDehydrogenase is: |
erythrocytes |
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Which group of isoenzymes areinvolved in the metabolism of more than 50% of all drug? |
Cytochrome P450 |