Csa

Overload of iron. Can cause fatigue and damage to the liver, joints, heart and pancreas. Treated by giving blood. AUTOSOMAL RECESSIVE

Red blood cells are misshapen. Can lead to chest or joint pain and infections, as well as anaemia. AUTOSOMAL RECESSIVE

Body makes faulty haemoglobin. Can be 'major' or 'minor'. African/Middle Eastern/Asian families. AUTOSOMAL RECESSIVE

AUTOSOMAL RECESSIVE. 1 in 25 background risk of being a carrier. Affects lungs and digestive system and can affect fertility.

Fault in storing too much copper which can affect liver and brain if untreated- however can be treated with chelation (penicilliamine). AUTOSOMAL RECESSIVE

Also known as factor 8 deficiency. Causes problem with blood clotting. X LINKED RECESSIVE meaning only males have it, and only females pass it on.

Also known as Factor 9 deficiency or Christmas Disease. Causes problem with blood clotting. X LINKED RECESSIVE meaning only boys have it and only girls can pass it on. Can be mild moderate or severe.

Slow progressive muscle weakness first affecting the legs and pelvis. X LINKED RECESSIVE. Less severe than Duchennes, very individual, life expectancy 40-50

Severe form of muscular problem usually onset in early childhood. X LINKED RECESSIVE. Life expectancy early 30s.

Causes intellectual disability and characteristic facial features. A common cause of autism. X LINKED DOMINANT, so females can be affected also.

X0. Only one working copy of the X chromosome. Girls with webbed necks, short stature, usually normal intelligence. Infertile.

XXY. Males with an extra X. Causes infertility and small testicles. Intelligence usually normal.

FSH/LH day 1-5 of cycle

Progesterone 7 day before period

Chlamydia/rubella serology

Over 35 is UKMEC 3

30-34 is 2

If over 35 and smoking, UKMEC 3

if under 35 and smoking, UKMEC 2

Need to have stopped for Over 1y to reduce

Migraine with aura, UKMEC 4

without aura, UKMEC2, unless it starts after starting the pill, where it's a 3

If VTE in family aged over 45, UKMEC 2.

if VTE in family under 45, UKMEC 3

If over 140/90, UKMEC 3

Remains UKMEC 3 if then well controlled

FH of breast cancer UKMEC 1 (unless BRCA positive in which case UKMEC 3)

Can restart COCP after 6w

3-6w can use COCP only if no other risk factors for VTE

If less than 5 days ago, and is now less than 5 days after earliest likely date of ovulation, advise Coil.

Unless, they've had other UPSI in same cycle (may need pregnancy test and then Oral EC)

If less than 96h, use Levonorgestrel. If BMI over 26 or weight over 70kg, double dose. Quickstart contraception.If between 96h and 120h, use Ulipristal. Wait 5 days, then start contraception.

If between 96h and 120h, use Ulipristal. Wait 5 days, then start contraception.

Start at 25

Every 3 years until 49

Every 5 years 50-74

50 to 70 every 3 years

Can be requested after that

1 in 25 get called back. 1 in 4 of those get diagnosed with Ca.

1x 1st degree under 40

1 1st/2nd of any age

3 2nd degree relatives

Bilateral breast ca

1st degree male breast ca

Jewish ancestry

Ovarian cancer

Ok if in days 1-5 of period.

If after this, needs additional contraception for 1 week

After 21 days

Clinic BP over 160/100

Home BP over 150/95

Clinic BP over 160/100

Home BP over 150/95

Refer all patients/contacts to GUM clinic

Metronidazole 400mg BD +Doxycycline 100mg BD for 14 days

Metronidazole 400mg BD for 7 days

Azithromycin 1g STAT

OR, Doxycyline 100mg BD for 7 days (14 if PID)

1g azithromycin.

Or doxycycline 100mg BD

risk age 20 = 1/1500, age 30=1/800, age 40=1/100

11-14w check; Combined Test. Calculated using maternal age, hormone levels, and nuchal fold. If "High Risk" i.e less than 1.150 chance, goes on to Chorionic Villous Sampling or Amniocentesis.