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13 Cards in this Set

  • Front
  • Back

Re emerging disease

Infectious agents that have been known for some time, had fallen to such low levels that they were no longer considered public health problems & are now showing upward trends in incidence or prevalence worldwide


Cholera

Vibrio cholerae

Lassa fever host

Rodent

Trend of infectious disease

1. Receded in Western countries 20th century


2. Urban sanitation, improved housing, personal hygiene, antisepsis & vaccination


3. Antibiotics further suppressed morbidity & mortality


4. 20th century- new & resurgent infectious diseases


5.Unusually large number- Rotavirus, Cryptosporidiosis, HIV/AIDS, Hantaviraus, Lyme disease, Legionellosis, and Hepatitis

Common features of infectious disease

All were caused by zoonotic pathogens


All spread by modern transportation


Most had Asian origin


Laboratory and clinical diagnoses were problematic


Poor communication among countries


Major economic impact

After natural disaster

Diarrhea


Acute respiratory infections


Malaria


Leptospirosis


Measles


Dengue fever


Viral hepatitis


Typhoid fever


meningitis


tetanus

Host factors to emergence

Human demographic change (inhabiting new areas)


Human behaviour (sexual & drug use)


Human susceptibility to infection (Immunosuppression)


Poverty & social inequality

Environment factor emergencr

Climate & changing ecosystems


Economic development & Land use (urbanization, deforestation)


Technology & industry (food processing & handling)


Deterioration in surveillance systems Others


Genetic drift/ genetic shift


Mass immunocompromisation Economic development


Breakdown of public health


Poverty and social inequality


Dam and irrigation system construction


Interracial marriage


Transmission of infectious agent

Animal/ population displacement


Climate patterns


Uncontrolled urbanization


Human behaviour


Antimicrobial drug resistance


Cause antibiotic resistance

Wrong prescribing practices


non-adherence by patients


Counterfeit drugs


Use of anti-infective drugs in animals & plants


Loss of effectiveness


Community-acquired (TB, Pneumococcal) & Hospital-acquired (Enterococcal)

Consequence antibiotic resistance

Prolonged hospital admissions


Higher death rates from infections


Requires more expensive, more toxic drugs


Higher health care costs

Disease spread diagram

Bioterrorism

Possible deliberate release of infectious agents by dissident individuals or terrorist groups


Biological agents are attractive instruments of terror- easy to produce, mass casualties, difficult to detect, widespread panic & civil disruption