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4 Cards in this Set

  • Front
  • Back

Km =

Vmax/2

Competitive inhibition

-increase in apparent Km


-no change in Vmax


-decreasing [S]


- Km= [S] (Vmax-Vi) / Vi

Noncompetitive inhibition

-decrease in Vmax


-increase in 1/ Vmax


-lowers the [ ] of active enzyme, therefore lowers Vmax


-Vmax = k3 [Et]


-directly proportional

Pharmaceutical and clinical relevance of enzymes