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50 Cards in this Set
- Front
- Back
Adverse symptoms of steroids |
Abd pain and tar stools |
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Cox enzymes are also known as what? |
PGH2 prostaglandins |
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Ibuprofen is reversible or non reversible inhibitor of cox pathway? |
Reversible |
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Is aspirin reversible or non reversible? |
Non |
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Ibuprofen is selective or non selective? |
Non- cox 1 causes the GI effects |
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Cox 2 does what? |
Inhibits pains and inflammation |
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Antipyretic effects are actions from what? |
Hypothalamus |
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Metformin |
Inhibits glucogenisis Increases insulin in muscles and tissues after meals Triglycerides and cholesterol |
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Gliptin increases what? |
Incretin |
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GLP is sucreated from? |
L cells |
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GLP slows what? |
Gastric emptying |
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GLP increases or decreases glucose? |
Decreases |
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GLP works in what cells? |
Alpha |
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Exenatide |
Like GLP- regulates glucose and insulin secretion |
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Alpha glycosides dose and when to give? |
50-100 with first bite of food |
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TZD side wffects |
Water retention Bladder cancer Bone fractures |
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Insulin peaks |
1,3,4, none |
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Insulin duration |
5,10, 12-24, 24 |
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Adverse effects of levothyroxine |
Tachycardia, angina I’m elderly |
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PTU side effects |
Fatal granulocytopenia |
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First sign of granulocytopenia |
Fever and sore throat |
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Vasculitis is a side effect of what med? |
PTU |
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Aplastic anemia is a side effect of what meds? |
PTU |
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Does PTU inhibit iodine? |
No, it converts t4 to t3 |
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What is the difference with PTU and methimazole? |
PTU works on thyroid and peripheral and methimazole only works in thyroid |
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What does methimazole inhibit? |
Thyroperoxidase |
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What cardiac med is most likely going to effect the kidneys? |
ACE |
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What is an effective cardiac med? |
Ramipril |
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What are involved in the pacemaker signals? |
Calcium channels |
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What are the classes of calcium channel blockers? |
Dihydropyridines Phenylalanine Benzothiazepine |
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Dihydropyridines exsamples |
Nifedipine and nicardipine-vasodialte smooth muscles |
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Phenylalanine |
Verapamil- effects heart: negative inotrophic and chronotrophic |
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Benzothiazepine exsample |
Diltiazem- combined effect of other two |
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Reflex tachycardia can be a problems with ischemic patients because?? |
Increased o2 demands |
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Amlodipine is what kind of CCB? |
Dihydropyridine |
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What’s contradicted in amlodipine? |
Grapefruit juice |
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Statins block what pathway? |
Hmg- coa |
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What happens when the liver can no longer produce cholesterol? |
Levels will fall |
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Fibric acid treat what? |
Triglycerides |
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Do not use fibrates in patients with what? |
Low HDL |
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Do not use fibrates in patients with what? |
Low HDL |
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Acid sequestrants |
Cholestyramine (cholybar, Olestyl) |
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Do not use fibrates in patients with what? |
Low HDL |
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Acid sequestrants |
Cholestyramine (cholybar, Olestyl) |
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Bile acids are excreted how? |
In stool |
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If reduced ejection fraction then use what? |
Aldosterone in addition to AcE and betas |
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Procanimide produce what after 6mths |
Antibiodies |
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Exsample of sodium glucose co-transporter |
Invonka |
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Exenatide (byetta) |
1hr prior to meal sub q |
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Tricor does what? |
Decreases LDL and triglycerides and increases HDL |