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10 Cards in this Set
- Front
- Back
FEMALE SEX HORMONESESTROGEN
l Produced in ?(3) l Regulated by ? l Stimulates ? l Stops growth - closes ? l Menstrual Cycle - growth of ? |
ESTROGEN
l Produced in ovaries, adrenal gland and testes l Regulated by FSH l Stimulates growth & development of sexual organs l Stops growth - closes epiphyseal plate l Menstrual Cycle - growth of endometrium and blood supply |
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FEMALE SEX HORMONES
ESTROGEN METABOLIC EFFECTS 4 |
ESTROGEN METABOLIC EFFECTS
l Retention of sodium and water l Alter glucose tolerance l Prevent negative calcium balance l Carcinogenic • Uterine • DES babies with cervical cancer • Breast |
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FEMALE SEX HORMONES
ESTROGEN THERAPEUTIC USE 6 |
ESTROGEN THERAPEUTIC USE
l Oral/patch contraception with a progesterone l Menopausal symptoms l Increase bone density (no longer approved for this use) l Atrophic vaginitis l Dysmenorrhea l Cancer - prostate |
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FEMALE SEX HORMONES
ESTROGEN SIDE EFFECTS |
ESTROGEN SIDE EFFECTS
l Nausea - tolerance develops l Mid cycle bleeding l Breast tenderness l Increased blood clotting • avoid in smokers • avoid BCP over age of 45 |
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FEMALE SEX HORMONES
SPECIFIC ESTROGEN RECEPTOR MODULATOR 3 1 ex? |
l Non-estrogen that stimulates estrogen receptor
l Indicated for increased bone density for those that cannot tolerate estrogens l example: Raloxifene (Evista®) |
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FEMALE SEX HORMONES
PROGESTERONE 5? |
PROGESTERONE
l Produced in corpus luteum after ovulation l Regulated by LH l Corpus luteum regresses after 14 days if ovum is not fertilized l Prepares endometrium for implantation l Increases basal body temp 1°C |
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FEMALE SEX HORMONES
PROGESTERONE THERAPEUTIC USE 5? |
PROGESTERONE THERAPEUTIC USE
l Uterine Bleed due to ovulatory failure l Dysmenorrhea l Contraception with or without estrogens l Protect uterus from estrogen induced cancer l Endometrial cancer |
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FEMALE SEX HORMONES
ORAL/PATCH CONTRACEPTIVES 4 |
l 99% effective
l Stops Ovulation l Cervical gland produces mucous so sperm cannot pass l Progesterone alone administered daily l Progesterone with an estrogen administered for 21 days |
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FEMALE SEX HORMONES
GENERAL INFORMATION 3 |
l Not effective during the first month of therapy
l If one dose is missed then double the next dose, if two doses is missed then double for two days l Discontinue for three months prior to pregnancy |
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FEMALE SEX HORMONES
Side Effects for bc 5 |
Side Effects
l Nausea/vomiting l Headache l Weight gain • Tolerance develops to all above l Acne • Lower incidence with tri-phasic birth control pills l Melasma |