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8 Cards in this Set

  • Front
  • Back

Broad categories of ovarian neoplasms?

Epithelial-stromal (benign, borderline, malignant)


Germ cell tumors


Sex chord-stroma


Mets to ovaries



Borderline epithelial-stromal cell tumors have good prognosis



What are the germ cell tumors of the ovary?

Germ cell tumors constitute approximately 20% to 30% of
all ovarian neoplasms. They are thought to be derived from
primitive totipotent germ cells and may appear to be undifferentiated
(dysgerminoma) or high-grade anaplastic carcinoma
(embryonal c...


Germ cell tumors constitute approximately 20% to 30% of
all ovarian neoplasms. They are thought to be derived from
primitive totipotent germ cells and may appear to be undifferentiated
(dysgerminoma) or high-grade anaplastic carcinoma
(embryonal carcinoma), or they may exhibit some
degree of differentiation resembling extraembryonic yolk
sac (endodermal sinus tumor), trophoblast (choriocarcinoma),
or combinations of the three embryonic germ layers
(teratoma).



Most germ cell tumors occur in children and
adolescents and account for two thirds to three quarters of
all ovarian tumors in these age groups.369 The large majority
are benign mature cystic teratomas curative by surgical
resection. The remainder are malignant tumors warranting
adjuvant radiation, chemotherapy, or both. Advances in
chemotherapeutic regimens for malignant germ cell tumors
have yielded overall 5-year survival rates of greater than
95%

____ ("___"): arise from post meiotic germ cell; mature fetal tissues; ____ is the most prevalent (skin, glial tissues)...also teeth, bone, adipose tissue, cartilage, respiratory and intestinal mucosa

Mature cystic teratoma (dermoid cyst); ectoderm

____: pre-meiotic oogonia; excellent prognosis; most common malignant germ cell tumor; age 20-30 year

Germ cell tumor: dysgerminoma (biomarkers?)

What makes up a immature teratoma?

immature fetal tissue;


mature + immature elements; primitive neuroepithelium; rapidly growing; peritoneal involvement; metastases

____: pre-meiotic oogonia; excellent prognosis; most common malignant germ cell tumor; age 20-30 years

Dysgerminoma (biomarkers?)

*Sex cord-stromal tumors: primitive sex cord/____ origin; functioning tumor with low grade malignancy.


What is it called in females and what does it secrete?

Mesenchyme



Granulosa cell tumor. Activity leads to hyperestrogenism; bleeding, breast enlargement, endometrial hyperplasia/carcinoma; hemorrhage, rupture;

Sex cord-stromal tumors: ____; a functioning tumor leading to androgenism; virilizing signs; abdominal symptoms; low or high grade malignancy


sertoli-leydig cell tumor