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16 Cards in this Set
- Front
- Back
adenoma type with nucleoli plus branching, L shaped dilated glands, mutated BRAF, dysplasia
large firm polyps with trunk, freckles on lips, palms, genitals |
sessile serrated adenoma
Peutz-Jegher's hamartomas |
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benign but dysplastic cells- arranged as crypts:
arranged as villi: shape of nuclei? where are they most common? |
tubular adenoma
villous adenoma cigar-shaped rectosigmoid area |
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Defect in the APC locus, thousands of tubular/villous adenomas develop in colon:
Polyposis coli with minor birth defects also: Colon polyps and brain tumors: |
Familial polyposis coli syndrome
Gardner's syndrome Turcot's syndrome |
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Colon cancer is usually what type of cancer?
Tumors in the cecum are likely to produce ______________. Eruption of multiple seborrheic keratoses is the "_________" sign and warns of a ____________ cancer. |
adenocarcinoma
iron deficiency anemia Leser-Trelat occult blood |
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Lakes of mucin containing signet ring cells:
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mucinous carcinoma
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Scarring of the liver, disrupts the liver's vascular architecture, fibrous bands dividing liver into nodules:
single-cell apoptosis of a hepatocyte, attacked by T-cell |
cirrhosis
councilman body |
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distinctive hepatocytes seen in chronic Hep B infection:
hemolysis, elevated liver enzymes, low platelets, serious complication of pregnancy: |
ground glass hepatocytes
HELLP syndrome |
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rope-like masses of altered cytokeratin and cell stress proteins (ubiquitin, etc)
Gilbert's and Crigler-Najjar result from a mutation in which gene? |
Mallory's hyaline
glucuronyl transferase |
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Why does a liver patient develop ascites?
What is the first clotting factor to go? cirrhosis with nodules smaller than 0.3 cm, fibrous-scar bands thin: |
increased serum albumin
VII micronodular |
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Micronodular cirrhosis affects the liver evenly or unevenly?
One common cause? Nodules >0.3 cm, fibrous bands thin: common causes? |
evenly
alcoholism macronodular Wilson's disease, galactosemia, a-1-antitrypsin deficiency |
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Eponym for hepatic vein thrombosis?
most common causes? Councilman bodies are common with what disease? |
Budd-Chiari
polycythemia vera, hypercoagulable state, hepatic carcinoma Viral hepatitis |
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transmitted fecal-oral, poor sanitation, endemic on Indian reservations:
world's most serious DNA-virus related problem, 300 million carriers, ROI transfusion, shared needles: |
Hep A
Hep B |
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autoimmune disease caused by Ab's against pyruvate dehydrogenase:
A common drug especially hard on the liver: "The death angel" mushroom: |
primary biliary cirrhosis
Acetomeniphen amanita phalloides |
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suppuration involving the bile ducts, underlying cause is almost always obstruction, neutrophils in bile ducts:
"anchovy paste" necrosis without inflammation, hyatid cysts: |
bacterial cholangitis
amebid abscesses |
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Fatty change to the Ito cells, stellate cell lipidosis:
giant mitochondria in alcoholic hepatitis: increased total body iron from any cause: |
Vitamin A overdose
Yokoo bodies hemosideriosis |
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hemosideriosis that damages liver parenchyma:
Classic triad of hemochromatosis: autosomal-recessive problem, too much copper in blood: |
hemochromatosis
liver trouble, DM, skin color change Wilson's disease |