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21 Cards in this Set
- Front
- Back
In relation to neutrophils, what is a LEFT SHIFT? |
The presence of immature neutrophils
(band neutrophils) |
|
In relation to neutrophils, what is a RIGHT SHIFT? |
The presence of older cells, post-maturity
(hyper-segemented neutrophils) |
|
In what situations might you see
hyper-segmented neutrophils / a RIGHT SHIFT? |
|
|
In what type of cell might you see canine distemper bodies? |
polychromatic cells |
|
What type of poikilocytosis is due to artifact? (3) |
1. Torocytes
2. Ovalocytes
3. Echinocytes / Crenation |
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What type of poikilocytosis is due to pathology? (3) |
1. spherocytes
2. ghost cells
3. eccentrocytes |
|
3 RBC abnormalities |
1. schistocytes
2. agglutination
3. rouleaux |
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A LEFT SHIFT in relation to neutrophils is
normally associated with what type of condition? |
Inflammatory condition |
|
What is a degenerative shift to the left? |
The number of immature, non-segmented
neutrophils EXCEEDS the number of segmented
neutrophils. |
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What does a degenerative left shift indicate? |
The inability of the bone marrow to produce more WBCs to respond to infection.
WBC count will begin to decline. |
|
proliferation pool |
bone marrow - producing cells |
|
storage pool |
mature cells stored in bone marrow and spleen
for future use. |
|
circulating pool |
cells circulate freely through blood until needed |
|
marginal pools |
cells stuck to or rolling along vessel walls |
|
tissue pools |
leukocytes that have left the blood vessels to go
to different parts of the body |
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What is a REGENERATIVE LEFT SHIFT? |
When there are more mature neutrophils
(segmented) than immature neutrophils |
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Name the 4 types of immature neutrophils that you might see in a degenerative left shift. |
1. band neutrophils
2. metamyelocytes
3. myelocytes
4. myeloblast |
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What does a regenerative left shift indicate? |
That the bone marrow is responding.
WBC count is increasing
Pools are not depleted. |
|
Why might you see a right shift? |
1. normal aging process
2. resolving chronic inflammation
3. more WBCs were utilized, so end result is increase in hyper segmentation or aging process. |
|
What condition would hyposegemented neutrophils appear in? |
Pelger-Huet anomoly |
|
How do neutrophils with Pelter-Huet anomaly appear, and what causes this? |
eye-glasses appearance
hypo-segemented
hereditary - cells function normally |