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186 Cards in this Set

  • Front
  • Back
Tricyclics
Elevil, Tofranil, Norpramin
DEPRESSION
budcat
takes 2-6 weeks for effect
MAOI
Marplan, Nardil, Parnate
DEPRESSION PHOBIAS ANXIETY
Hypertensive crisis - caused when taken with trycyclics- DO NOT use with tricyclics
- Tyramine precautions
SSRI
Prozac, Paxil, Zoloft, Luvox, Celexa
depression, anxiety, panic, aggression, anorexia, OCD
Serotonin Syndrome
2-4 weeks to take effect
do NOT use with MAOI--> HTN crisis
SSRI
Serotonin Syndrome
- rapid onset of altered mental status
- agitation
- myoclonus
- hyperreflexia
- fever, shivering
- diaphoresis
- ataxia
- diarrhea
* St. John's Wort
Atypical
Desyrel
Remeron
Effexor
- takes 2-4 weeks to be effective
Anti-anxiety side-Effects
sedation
drowsiness
Antidepressant Side Effects
Anticholinergic effects
postural hypotension
MAOI SE
hypertensive crisis
Lithium Side Effects
LFT
Blood Tests
Phenothiazines
EPS
Tardive dyskinesia can be permanent if not assessed early
Phenothiazines
photosensitivity
MAOI
require diet precautions- avoid tyramine rich foods
Antimanic/Mood Stabilizing Drugs
Lithium
Anticonvulsants
Antipsychotics
Sedatives
Lithium
esp. Manic phase
weight gain, Hypothyroidism
maintain .5-1.5 levels
Sodium- keep sal usage consistent
do NOT use with diuretics
Valproic Acid (DEpakene)
Gi distress, Hepatotoxicity
Tremor, Sedation, dizzy
administer with food
serum levels: 50-125
Carbamazepine
Anticonvulsant
alternative to lithium
dizziness, ataxia
Atypical Antidepressents are also used for
Mania
antipsychotic Drugs
Phenothiazines ( typical)- treat positive only
Atypical- positive and negative
Chlorpromazine
Fluphenazine
Haloperidol
Chlorprothixine
Thiothixene
Anti-psychotic ( phenothiazines)
Antipychotic Adverse Reactions
drowsiness
orthostatic hypotension
EPS
Anticholinergic
Photosensitivity
NMS
EPS
Pseudo-Parkinsonism
Akathisia
Dystonia
Tardive Dyskinesia
Haldol
severe EPS
can be given every 4 weeks (decanote)
Orap
Tourete's Syndrome
Atypical Antipsychotics
Risperidone
Olanzapine
Quetipine
Aripiprazole
Ziprasidone
Clozapine
Atypical Antipsychotics
treat positive and negative
fewer side effects
Atypical Antipsychotics Adverse Reactions
RIsperdal- NMS, EPS
Zyprexia- drowsiness, dizzy
Seroquel- EPS, anticholinergic
Clozaril-AGRANULOCYTOSIS
( check WBC count)
Parkinsonism
rigidity
shuffling gait
pill-rolling
tremors
mask-like face
Akithesia
inability to sit still
give Inderal
Dystonia
limb and neck spasms
uncoordinated, jerky movements
- give IM anticholinergics
CAB protocol
for EPS symptoms
Cogentin, Artane Benadryl
Tardive Dyskinesia
involuntary tongue/lip movements
blinking
choreiform movements of limbs and trunk
- PERMANENT side effect
Photosensitivity
exposed skin turns blue
color changes in eyes- no vision impairment
NMS
life-threatening emergency
high fever
tachycardic
stupor
increased respirations
sever muscle rigidity
Serotonin Syndrome
confusion
disorientation
autonomic dysfunction
Anticholinergic Effects
BUDCAT
Bluured vision
urinary retention
dry mouth
constipation
A?
tachycardia
Antabuse
Aversion Therapy
SERVERE SE if alcohol consumed: NV, hypotension, headache, rapid pulse and respiration
READ LABELS!!!
Alcohol Withdrawal
Librium, Ativan
Opiate Withdrawal
watery eyes
runny nose
dilated pupils
anxiety
insomnia
tachycardia
NVD
Opiate OD
respiratory depression--arrest
circulatory depression--arrest
unconsciousness---coma
death
Opiates Effect
physical and mental deterioration
rapid tolerance
impaired judgement
Cocaine Withdrawal
depression
fatigue
disturbed sleep
anxiety
psychomotor agitation
Cocaine OD
tachy
pupilary dilatation
increased BP
cardiac arryhtmias
perpiration, chills
NV
Cocaine Effects
psychological dependence
tolerance within hours or days
Amphetamines Withdrawal
DEpression
fatigue
disturbed sleep
Amphetamines OD
restlessness
tremors
rapid respiration
confusion
assaultive behavior
hallucinations
panis
Amphetamines Effect
Paranoid delusions
Hallucinogenics Withdrawal
NONE
Hallucinogenics OD
Panic
Psychosis
Hallucinogenics Effect
flashabcks
impaired judgement
BZA Withdrawal
tremors
agitation
anxiety
abdominal cramps
grand mal seizures
BZA OD
drowsiness
confusion
hypotensoin
coma--> death
Chemically Dependent Client
Group therapy
support groups
Alzheimer's Meds
Tacrine
Donepezil
Rivastigmine
Galantamine
Concerta ( ER)
Adderall
AZ Adverse Reactions to Meds
Nausea and Diarrhea
Cognex: considerable GI distress and elevated liver enzymes
AZ Teaching for Meds
NO anticholinergic meds!
not with severe liver impairment
take with meals to avoid GI upset
do NOT discontinue abruptly
AZ Alternative meds
Atypical Antipsychotics
-Risperidone, Quietapine, Olanzapine
not CLozaril bc of side effects
Mood Stabilizers, Anti-anxiety as indicated
Penicillin G
gram positive bacteria
- diarrhea, GI reactions
- use with caution with allergies to cephalosporins
-observe for 30 minutes following parenterla admin.
-taken on an empty stomach
-alters contraceptive effectiveness
Ampicillin
Broad Spectrum
-rash (reactions)
- contraindicated for those allergic to penicillin
Tetracycline
Photosensitivty reaction
- decrease oral contraceptives
- avoid antacids/milk
-yellow/brown discoloration and growth retardation
Adrenergics.Sympathomimetics
- Bronchodilators
Epinephrine
Isoproteronol
Albuterol
Terbutaline
levabuterol
Adverse Reactions to Adrenergics/Sympathomimetics for Bronchodilation
Anxiety
increased HR
NV
Urinary retention
Adrenergics/Sympathomimetics Nursing COnsiderations
- check HR
- monitor for urinary retention
- proper use of inhaler
-bronchodilator before steroid inhaler
-may cause sleep disturbance
Methylxanthines
Aminophylline/Theophylline
- GI distress, Sleeplessness, Cardiac Dysrhytmias, Hyperactivity
: with food
:avoid caffeine
:therapeutic range: 10-20
:crosses placenta
Corticosteroids
Prednisone
Solu-Medrol
Beclomethasone
Pulmicort
Flovent
Azmacort
AeroBid
Corticosteroids (Anti-Inflammatory)
Adverse Reacts:
- cardiac dysrhytmias with long term use
Nursing:
- instruct in proper use
* see Endocrine Meds
Anticholinergics for Bronchodilation and Rhinorhea control
Atrovent
- dry mouth, blurred vision, cough
DO NOT EXCEED 12 DOSES in 24 HOURS!
Combination Productsfor Asthma
Advair
Tuberculosis Meds
INH
Rifampin
Ethambutol
Isoniazid (INH)
Side Effects:
-NV
-RARE- neurotoxicity, hepatotoxicity
- administer with B6
-active TB patients
-crosses BBB
Rifampin
-possible orange urine
Nitrates
nitroglycerin
Isordil
Imdur
Nitrates Indications
Angina prophylaxis
acute attack
reduces vascular resistance
nitrates Adverse Reactions
HEADACHE
flushing
dizziness
weakness
hypotension
nausea
Nitrates Nursing COnsiderations
- monitor relief
- client rests
-monitor vitals
- store in original container
- replace NTG every 6 months
Beta Blockers for Angina
Propanolol
Atenolol
Nadolol
Beta Blocker Indications
Angina prophylaxis
reduces o2 demand
Beta Blcoker Adverse Reactions
fatigue
lethargy
hallucinations
impotence
bradycardia
hypotension
Heart Failure
Wheezing
Beta Blockers Nursing Indications
Monitor APICAL heart rate
assess decreased BP
DO NOT STOP ABRUPTLY
Calcium Channel Blockers
Verapamil
Nifedipine
Diltiazem
CCB Indications
angina prophylaxis
CCB Adverse Reactions
Dizziness
hypotension
headache
syncope
peripheral edema
HYPOKALEMIA
Dysrhythmia
HF
CCB Implications for Nurses
monitor Potassium ( hypokalemia)
swallow pills whole
do not stop abruptly
take 1 hour before meals or 2 hours after meals
Anti-Lipid Meds
Bile Sequestrants
Statins
Niacin
Bile Sequestrants
Welchol
falulence, belching
Statins
Lipitor, Zocor
- may elevate liver enzymes!
- Rhabdomyalysis
*monitor LFT every 6 months
*avoid grapefruit juice
*report muscle tenderness
Niacin
*Flushing
- upper GI distress
- give aspirin before to avoid flushing
Meds for Acute Angina
Nitroglycerin
Not appropriate for Acute Angina
Digoxin
Atropine
Propanolol
Digoxin
increases the strength and contractility of the heart muscle
Atropine
increases HR
-Vagal nerve suppresion
the Vagal nerve suppresses the heart rate
Propanolol
LONGTERM management of angina
- controls vasoconstriction
Ck-MB
onset: 2-4 hours
Peak: 12-20 hours
returns: 48-72 hours
Troponins
Onset: 1 hour post-injury
Peak: 10-24 hours
Normal: 5-14 days
MI drugs
MOrphine SUlfate
Nitroglycerin
beta blockers
CCB
aspirin
antiplatelet aggregates
Fibrinolytic Therapy
( as soon as a positive troponin after MI)
Streptokinase
Reteplase
Alteplase
Reteplase
fibrinolytic
- for coronary thrombus
- can cause hypotension
- obtain baseline PT, PTT, CBC
- avoid needle punctures
Alteplase
DVT, PE, Coronary thrombosis
- interacts with heparin-->increases risk for bleeding
- does NOT work systemically
Antihypertensive Pharm therapy side effects
IMpotence
insomnia
Diuretics
Thiazides- K-wasting
Loop- K-wasting
K-Sparring
Combination
Thiazides ( diuretics)
HCTZ
- decreases fluid volume
HYPOKALEMIA
sexual dysfunction
*Postural Hypotension?
*Caution with renal failure or taking lithium
**Hypokalemia increases risk for Digitalis toxicity
*Adminitster K supplements
HYPOKALEMIA Symptoms
dry mouth
thirst
weakness
drowsiness
lethargy
muscles aches
tachycardia
Loop Diuretics
Furosemide, Bumetanide
- hypokalemia
- sexual dysfunction
* RAPID volume depletion and electrolyte depletion
*same with thiazides
Potassium Sparing Diuretics
Spironolactone
- Hyperkalemia
- Gyencomastia
**watch with NSAID or ACE use
** give after meals to decrease GI stress
Anti-Hypertensives: Alpha Adrenergic Blockers
Prazosin
Carvedilol
decreases BP without reflex tachy/bradycardia
- Adverse Reactions:HF, Ventricular dysrhythmias
orthostatic hypo
Contrindications:
HF
Heart Block
COPD
*
Beta Blockers for Anti-HTN
Metoprolol, Propanolol,
- blocks SNS
- slower HR
- lowers BP
- reduces o2 consumption during MI
*do not d/c abruptly
*watch for SOB
*masks symptoms of hypoglycemia
Clonidine ( Catapres)
*watch for reboudn HTN
* caution with position changes
- lowers BP
Vasodilators
Hydralazine, Minoxidil
decreases BP by decreasing vascular resistance
- headache, fluid retention
*observe for peripheral edema
Angiotensin II Antagonists
Losartan, Valsartan
-Adv. Rxn: hypotension, renal failure
*monitor liver enzymes
ACE-Inhibitors
Anti-HTN
"prils"
- suppress RAAS
*useful with diabetics
Adv. Rxn: proteinuria, skn rash, cough
*observe for ARF
*routine renal function tests
*remain in bed 3 hours after first dose
CCB for anti-HTN
Diltiazem, Nifedipine, Verapamil
decreased conduction
Adv. Rxn.: headache, constipation, tachy, HF
*Limit caffeine
*before meals
*avoid grapefruit juice
Anti-Coagulants
Heparin, Warfarin
Heparin Sodium
antagonist to thrombin
Adv.Rxn: hemorrhage, agranulocytosis, keukopenia, hepatitis
*PTT
*Antagonist: Protamine Sulfate
WArfarin ( Coumadin)
Adv. Reaction:
- hemorrhage
-agranulocytosis
- leukopenia
- hepatitis
*PT
*avoid sudden changes in Vitamin K input
Antagonist: Vitamin K
Antiplatelet Agents
Plavix, LMWH
Plaxiv ( Clopidogrel)
short term use after interventions
intolerant to aspirin
Adv. Rxn:
- Pancytopenia
- Hemorrhage
- GI irritation, bleed

*monitor CBC
LMWH (lovenox)
DVT prevention
- hemorrhage
- GI irritation, bleeding
*monitor for bleeding
*subq
*monitor CBC
*use soft toothbrush
Drugs that cause Dysrhythmias
Digoxin
Quinidine
Caffeine
Nicotine
Alcohol
Antiarrhythmics
Quinidine, Lidocaine, Inderal, Verapamil, Atropine
Digoxin, Epinephrine, Natrecor
Propanolol for dysrhythmias
Supraventricular and ventricular tachy-dysrhythmias
*contraindicated in COPD and Athsma
Amiodarone
Inotropic
ventricular dysrhythmias
*wear suncreen and glasses outside- Photophobia
Atropine for dysrhythmias
for bradycardia
Adv. Reaction: chest pain, urinary retention, dry mouth
*monitor HR and rhythm, assess for chest pain
*assess for urinary retention
*avoid with use with glaucoma
Digoxin
Atrial Fib
Supraventriculr dysrhythmias
Adv. Rxn: bradycardia, dysrhythmias, anorexia, NVD, visual disturbances
*report signs of toxicity (hypokalemia increases risk)
*causes HYPERCALCEMIA
Epinephrine
cardiac arrest
Adv. Rx,: tachy, HTN
- impaired renal function--> toxicity
*monitor BUN and creatine
*monitor vitals
Natrecor
ADHF
- hypotension is side effect
*many drug-drug rxns
*as diuress occurs, monito electrolytes (K)
Wihhold digitalis if:
HR < 60 bpm
Digitalis
Side effects increased when hypokalemic
SLOWS the HR
hold if: <60 or >120
Signs of DIgitalis Toxicity
bradycardia
tachycardia
dysrythmias
NV
headache
Antacids-

(Anti-ulcer)
Maalox, Mylanta
- neutralizes stomach acid
Adv. Rxn.: Constipation, DIarrhea, Drug Interactions
*AFTER MEALS
H2- Antagonists

(Anti-Ulcer)
Zantac, Tagamet, Pepcid
- prophylactic tx
*no smoking
*expensive
@ risk for developing ulcers
on corticosteroids
stressed
Proton Pump INhibitors

(Anti-Ulcer)
"prazole's"
- tx of erosive esophigitis
Adv. rxn:
- abdominal pain, hepatic damage, pancreatitis, gastroenteritis
* BEFORE MEALS
* do NOT CRUSH/CHEW
Add'l Drugs (Anti-Ulcer)
Prokinetic Drugs
Antimetics
Cough Suppressants
Stool Softeners
Meds that increase risk for PUD
Salicylates (aspirin)
NSAIDS ( ibuprofen)
Corticosteroids in high doses
Resperine (anti-HTN)
Anticoagulants
Drugs for Inflammatory Bowel DIseases
- Crohn's
- UC
Steroids
Anti-diarrheals
sulfasalazine (azulfinide)
LActulose (Cephulac)
- Encephalopathy
decreases ammonia levels and bowel pH
Adv. Rxn: Diarrhea
* observe for diarrhea
*monitor ammonia levels
Thyroid Storm Meds
Propylthiouracil (PTU)
Methimazole (Tapazole)
Propanolol (indural)- decreases excessive sympathetic stimulation
THyroid Ablation therapy
PTU/ Methimazole
- blcosk synthesis of t3/t4
- given over months
- makes them euthyroid
- given to prepare for thyroidectomy
Radiation for THyroid
Iodine 131
- destroys thyroid cells
- GI irritation ( vomiting-reactive)
- on radiation precautions
Thyroid Preparations
Synthroid
Cytomel
Armour Thyroid
Synthroid
increases metabolic rates
synthetic T4
Adv. Rxn:
- anxiety, insomnia, tremors, tachy, palpitations, angina, dysrhythmias
*check serum hormone levels
*Check BP/pulse
*Avoid foods with iodine
*initiate cautiously in clients with cardiovascular disease
Corticosteroids for Endocrine Disorders
Hydrocortisone, Prednisone, Dexamethasone
Corticosteroids
Hormone replacement
Severe rheumatoid arthritis
autoimmune disorders
Corticosteroids Adverse Reactions
impaired wound healing
abnormal fat deposition
HYPERGLYCEMIA
hirsutism
moon face
osteoporosis
**symptoms of Cushing's if OD
Corticosteroids Nursing IMplications
*wean slowly
monitor K, Glucose and Na
(can become diabetic)
Weigh dailiy ( report if 5 lb/week gained)
give with antiulcer drugs or food
monitor BP and pulse
*Cushings syndrome symptoms teaching
sudden withdrawal of corticosteroids =
Addison's disease
Addison Crisis meds
IV glucose
parenteral glucocorticoids
- large fluid volum replacement
More Addison Crisis
- rapid infusion of fluids
- IV glucose
- PARENTERAL HYDROCORTISONE
- Aldosterone replacement
= Fludrocortison Acetate(Florinef) PO + Sodium Chloride ( salt) if Na deficit
Take steroids with
meals to avoid GI upset
(if prolonged--call dr)
Oral Hypoglycemics
Sulfonylureas (Glipizide)
Biguinides ( Metformin)
Alpha-Glucosidase Inhibitors (Precose, Glyset)
Thiozolidinedoines (Avandia, Actos)
Meglitindes ( Prandin)
Combo ( Glucovance)
Sulfonylureas
"ide's"
- stimulates insulin release
- glucose take up easier
Adv. Rxn.: heartburn, constipation, agranulocytosis
*given once daily with first meal
*elderly or on Beta Blockers- hard to detect
Metformin ( Glucophage)
-Biguinides
inhibit hepatic glucose production and increase sensitivity of peripheral tissue to insulin
* ER tablets should be taken with evening meal
*renal or Liver disease?
*not with Iodine contrast media
Avandia/Actose
Thiazolidinediones
- decreases insulin resistance
*weight gain and incr. cholesterol
*may precipitate HF
Rapid Acting Insulin
Lispro/ Insulin Aspart
Onset: 15 minutes
Peak: 2-4 hours
*give within 15 minutes of a meal
Short Acting Insulin
Regular (human)
Onset: 30-60 minutes
Peak: 2-3 hours
*CAN BE GIVEN IV
Intermediate Acting INsulin
NPH, Humulin
Onset: 1-2 hours
Peak: 6-12 hours
Mixtures: rapid Acting with Regular
Regular@ 30%
NPH @ 70%
Long Acting Insulin
Lantus
Onset: 1 hour
Peak: none
*give at bedtime
basal insulin
DO NOT MIX
do not shake!
Use with caution in NPO client
Anemia-inducing drugs
Salicylates
Thiazides
Diuretics
*Lead exposure
*insecticide exposure
Blood Products
Packed RBC
frozen RBC
Platelets
FFP (fresh frozen plasma)
Albumin
Fe preparations
with meals to decrease gastric irritation
B12 and folic acid
ORALLY
*except pernicious anemia- parenteral
Parenteral Iron
Z-track - prevents staining skin
use air bubble to avoid withdrawing med into subq
do NOT use deltoid
do NOT massage injection site
Syphillis
Penicillin G
Gonorrhea
Ceftriaxone
Chalmydia
Tetracycline
Trichomoniasis
FLagyl
Candidiasis
Monistat
Clotrimazole
Nystatin
Herpes
Acyclovir
HPV
podophyllum
Oxytocin (pitocin)
Uterine Stimulant-
- for uterine antony
AdvRxn:
- afterpains inmultipara
- HTN
*after placenta delivery
*may stimulate let-down milk reflex and flow of milk when engorged
Methergine
for uterine antony ( a uterine stimulant)
AdvRnx: HTN
*.2 mg --> .2 mg q4-6
*do not use if HTN or preeclamptic
*take BP prior ( if higher than 140/90- HOLD- notify dr)
Prostaglandin F2
(hemabate)
uterine stimulant
- for uterine antony
AdvRxn: headache, NV, fever, bronchospasm, wheezing
*contrindicated for asthma
*check temp every 1-2 hours
*auscultate breath sounds frequently
Prophylactic Eye Care
Erythromycin
*after 1 minute may wipe away excess
- for tx of opthalmia neonatorum and Chalmydia conjuntivitis
Silver NItrate
- gonorrhea exposure to eyes
ADVrxn: staining of skin
red, puffy eyes
*do NOT irrigate eyes after instillation
*mandatory in the US
Birth Analgesics
Meperidine
Fentanyl
Morphine Sulfate
Meperidine
Fentanyl
Morphine Sulfate
AdvRxn: respiratory depression, fetal narcosis, hypotension, itching, urinary retention
*do not admin if respirations < 12
*NARCAN
Bisocodyl (dulcolax suppository)
constipation after delivery
AdvRxn: cramping
*effective in 15 min- 1 hour
Docusate Sodium (Colace)
for constipation
or painful defacation with 4th degree tear
-abdominal cramping
*encourage increased fluid intak
*results within 1-3 days of continual use
RhoGAM
prevention of isoimmunization with next pregnancy
*give to Rh- women
@ 28 weeks (Rh- with a negative antibody titer)
*with Rh + newborn
*within 72 hours of delivery
**is a blood product
- checked by 2 nurses
- syringe returned to lab
- not given to mother with positive Indirect Coombs--she is already sensitized and has developed antibodies
Rubella vaccine
Rubella titer <1:10
*before discharge
*ok to breastfeed
- informed consent
**avoid pregnancy for 3 months
Needs for RhoGAM
Rh- mom with Rh+ baby
Negative Direct Coomb's test
(if positive) she is already sensitized
Bisocodyl (dulcolax suppository)
constipation after delivery
AdvRxn: cramping
*effective in 15 min- 1 hour
Docusate Sodium (Colace)
for constipation
or painful defacation with 4th degree tear
-abdominal cramping
*encourage increased fluid intak
*results within 1-3 days of continual use
RhoGAM
prevention of isoimmunization with next pregnancy
*give to Rh- women
@ 28 weeks (Rh- with a negative antibody titer)
*with Rh + newborn
*within 72 hours of delivery
**is a blood product
- checked by 2 nurses
- syringe returned to lab
- not given to mother with positive Indirect Coombs--she is already sensitized and has developed antibodies
Rubella vaccine
Rubella titer <1:10
*before discharge
*ok to breastfeed
- informed consent
**avoid pregnancy for 3 months
Needs for RhoGAM
Rh- mom with Rh+ baby
Negative Direct Coomb's test
(if positive) she is already sensitized