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77 Cards in this Set

  • Front
  • Back

anti-

opposite

capsa-

a box

exo-

out, outside, without

-genesis

origin, birth

helic-

a spiral

intro-

within

liga-

bound or tied

lyso-

loosen

lyto-

loosen

muta-

change

-phage

to eat

poly-

many

retro-

backward

semi-

half

trans-

across

virul-

poisonous

adenine (A)

a double-ring nitrogenous base found in DNA and RNA

AIDS (acquired immunodeficiency syndrome)

the late stages of HIV infection, characterized by a reduced number of T cells and the appearance of characteristic opportunistic infections

anticodon

on a tRNA molecule, a specific sequence of three nucleotides that is complementary to a codon triplet on mRNA

A site

one of two of a ribosome's binding sites for tRNA during translation. It holds tRNA that carries the next amino acid in the polypeptide chain. (A stands for aminoacyl tRNA)

bacteriophages

a virus that infects bacteria; also called a phage

capsid

the protein shell that encloses a viral genome

codons

a three-nucleotide sequence in mRNA that specifies a particular amino acid or polypeptide termination signal; the basic unit of genetic code

conjugation

the union (mating) of two bacterial cells or protist cells and the transfer of DNA between the two cells.

cytosine (C)

a single-ring nitrogenous base found in DNA and RNA

deoxyribonucleic acid (DNA)

a double-stranded helical nucleic acid molecule consisting of nucleotide monomers with deoxyribose sugar and the nitrogenous bases adenine, cytosine, guanine, and thymine. capable of replicating, it is an organism's genetic material.

DNA ligase


an enzyme, essential for DNA replication, that catalyzes the covalent bonding of adjacent DNA polynucleotide strands. it is used in genetic engineering to paste a specific piece of DNA containing a gene of interest into a bacterial plasmid or other vector.

DNA polymerases

a large molecular complex that assembles DNA nucleotides into polynucleotides using a preexisting strand of DNA as a template

double helix

the form of native DNA, referring to its two adjacent polynucleotide strands interwound into a spiral shape

emerging viruses

a virus that has appeared suddenly or has recently come to the attention of medical scientists

exons

the part of a gene that becomes part of the final messenger RNA and is therefore expressed

F factor

a piece of DNA that can exist as a bacterial plasmid. it carries genes for making sex pili and other structures needed for conjugation, as well as a site where DNA replication can start. F stands for fertility

frameshift mutations

a change in genetic material that involves the insertion or deletion of one or more nucleotides in a gene, resulting in a change in the triplet grouping of nucleotides

genetic code

the set of rules that dictates the amino acid translations of each mRNA nucleotide triplet

guanine (G)

a double ring nitrogenous base found in DNA and RNA

HIV (human immunodeficiency virus)

the retrovirus that attacks the human immune system and causes AIDS

introns

an internal, noncoding region of a gene that does not become part of the final messenger RNA molecule and is therefore not expressed

lysogenic cycle

a type of bacteriophage replication cycle in which the viral genome is incorporated into the bacterial host chromosome as a prophage. new phages are not produced, and the host cell is not killed or lysed unless the viral genome lease the host chromosome

lytic cycle

a type of viral replication cycle resulting in the release of new viruses by lysis (breaking open) of the host cell

messenger RNA (mRNA)

the type of ribonucleic acid that encodes genetic information from DNA and conveys it into ribosomes, where the information is translated into amino acid sequences

missense mutation

a change in the nucleotide sequence of a gene that alters the amino acid sequence of the resulting polypeptide. in this, a codon is changed from encoding one amino acid to encoding another.

molecular biology

the study of biological structures, functions, and heredity at a molecular level

mutagenesis

the creation of a change in the nucleotide sequence of an organism's DNA

mutagens

a chemical or physical agent that interacts with DNA and causes a mutation

mutation

a change in the genetic information of a cell; the ultimate source of genetic diversity. it can also occur in the DNA or RNA of a virus

nonsense mutations

a change in the nucleotide sequence of a gene that converts an amino-acid-encoding codon to stop a codon. this results in a shortened polypeptide

nucleotides

a building block of nucleic acids, consisting of a five-carbon sugar covalently bonded to a nitrogenous base and one or more phosphate groups

P site

one of two of a ribosome's binding sites for tRNA during translation. it holds the tRNA carrying to growing polypeptide chain (P stands for peptidyl tRNA)

phages

a virus that infects bacteria

plasmid

a small ring of independently replicating DNA separate from the main chromosome(s). they are found in prokaryotes and yeasts

polynucleotide

a polymer made up of many nucleotide monomers covalently bonded together

prions

an infectious form of protein that may multiply by converting related proteins to more of these. they case several related diseases in different animals, including scrapie in sheep and mad cow disease

promoter

a specific nucleotide sequence in DNA located near the start of a gene that is the binding site for RNA polymerase and the place where transcription begins

prophage

phage DNA that has inserted by genetic recombination into the DNA of a bacterial chromosome

retrovirus

an RNA virus that reproduces by means of a DNA molecule. it reverse-transcribes its RNA into DNA, inserts the DNA into a cellular chromosome, and then transcribes more copies of the RNA from the viral DNA. HIV and a number of cancer-causing viruses are these.

reverse transcriptase

an enzyme encoded and used by retroviruses that catalyzes the synthesis of DNA on an RNA template

ribosomal RNA (rRNA)

the type of ribonucleic acid that, together with proteins, makes up ribosomes; the most abundant type of RNA in most cells

ribosomes

a cell structure consisting of RNA and protein organized into two subunits and functioning as the site of protein synthesis in the cytoplasm. in eukaryotic cells, the subunits are constructed in the nucleolus

RNA polymerase

a large molecular complex that links together the growing chain of RNA nucleotides during transcription, using a DNA strand as a template

RNA splicing

the removal of introns and joining of exons in eukaryotic RNA, forming an mRNA molecule with a continuous coding sequence; occurs before mRNA leaves the nucleus

R plasmids

a bacterial plasmid that carries genes for enzymes that destroy particular antibiotics, thus making the bacterium resistant to the antibiotics

semiconservative model

type of DNA replication in which the replicated double helix consists of one old strand, derived from the old molecule, and one newly made strand

silent mutation

a mutation in a gene that changes a codon to one that codes for the same amino acid as the original codon. the amino acid sequence of the resulting polypeptide is thus unchanged

start codon

on mRNA, the specific three-nucleotide sequence (AUG) to which an initiator tRNA molecule binds, starting translation of genetic information

stop codon

in mRNA on of the three triplets (UAG, UAA, UGA) that signal gene translation to stop

sugar-phosphate backbone

in a polynucleotide (DNA or RNA strand), the alternating strand of sugar and phosphate to which nitrogenous bases are attached

terminator

a special sequence of nucleotides in DNA that marks the end of a gene. it signals RNA polymerase to release the newly made RNA molecule and then to depart from the gene

thymine (T)

a single-ring nitrogenous base found in DNA

transcription

the synthesis of RNA on a DNA template

transduction

the transfer of bacterial genes from one bacterial cell to another by a phage

transfer RNA (tRNA)

a type of ribonucleic acid that functions as an interpreter in translation. each on has a specific anticodon, picks up a specific amino acid, and conveys the amino acid to the appropriate codon on mRNA

transformation

the incorporation of new genes into a cell from DNA that the cells takes up from the surrounding environment.

translation

the synthesis of a polypeptide using the genetic information encoded in an mRNA molecule. there is a change of "language" from nucleotides to amino acids

triplet code

a set of three-nucleotide-long "words" that specify the amino acids for polypeptide chains.

uracil (U)

a single-ring nitrogenous base found in RNA

viroids

a plant pathogen composed of molecules of naked, circular RNA several hundred nucleotides long

virus

a microscopic particle capable of infecting cells of living organisms and inserting its genetic material. they are generally not considered alive because they do not display all of the characteristics associated with life