Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
3 Cards in this Set
- Front
- Back
|
Type 3 hypersensitivity |
• Mediated by immune complexes• Immune complexes are formed when antibodies bind to free/ soluble antigen (self or non-self)•The immune complexes deposit in blood vessels• cause vasculitis and vessel wall damage by activating complement system Both type 2 & type 3 hypersensitivity involve antibodies (IgM {IgG) that attack self antigen and non self antigen as well |
|
|
In SLE, immune complex deposit in sites like |
Kidney( causing glomerulonephritis) Joints ( causing arthritis) That's why it's called "SYSTEMIC" |
|
|
Examples of type 3 hypersensitivity reaction |
Systemic Lupus Erythematosus(SLE) Serum sickness |
