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11 Cards in this Set
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Opioids/Narcotics
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Pain Relief; choose based on potency, onset/duration time and method of metabolization (keep byproducts and their toxicity in mind).
Opioids / Narcotics Group 4 |
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Opioids
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Any opium-containing substance that is produced naturally in the brain.
Similar in effect or properties to opium but not derived from opium. An opioid is a chemical that works by binding to opioid receptors, which are found principally in the central nervous system and the gastrointestinal tract. The receptors in these two organ systems mediate both the beneficial effects and the side effects of opioids. The analgesic (pain relieving) effects of opioids are due to decreased perception of pain, decreased reaction to pain as well as increased pain tolerance. The side effects of opioids include sedation, respiratory depression, and constipation. Opioids can cause cough suppression, which can be both an indication for opioid administration or an unintended side effect. |
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Narcotics
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Agents that benumb or deaden, causing loss of feeling or paralysis.
Something that soothes, induces sleep, relieves pain or stress, or causes a sensation of mental numbness. |
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Morphine
Drug (trade name) |
Morphine
Opioids / Narcotics Group 4 |
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Morphine
Class |
Natural
Opioids / Narcotics Group 4 |
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Morphine
Uses |
IV, epidural,
spinal--Pain relief Opioids / Narcotics Group 4 |
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Morphine
[ Supplied ] |
10mg/ml
Opioids / Narcotics Group 4 |
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Morphine
Dosing--card |
0.1mg/kg (0.05-0.15)
Opioids / Narcotics Group 4 |
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Morphine
Dosing--Stever |
Intraop 0.1-1mg/kg IV; Postop 0.03-0.15mg/kg IV
Opioids / Narcotics Group 4 |
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Morphine
Caution |
Depression of ventilation; PONV, Biliary spasm, Itching, Histamine release
Opioids / Narcotics Group 4 |
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Morphine
Notes |
IV/IM, low lipid solubility-->slower onset(15-30m), Potency 1, 2-10mg peak effect 45-90m, duration 3-4h, metab.
in liver/kidnerys, active metabolite almost as potent as morphine, so will accumulate & last longer in pt w/ kidney/renal disease. Opioids / Narcotics Group 4 |