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9 Cards in this Set
- Front
- Back
What is inoculation? |
Purposely infecting a person with a mild disease (Variola minor) to protext them against a severe disease (Variola major) |
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What did Edward Jenner discover? |
-Noticed milkmaids seldom get smallpox, this is because they are already infected with cowpox. -Inoculated someone with cowpox and this person was then injected with smallpox and remained asymptomatic- birth of vaccination! |
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What are the 3 strategies that the immune system uses to protect the body from infection? |
1. protective barriers 2. innate immune response 3. adaptive immune response |
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What does sebum do? (secreted by sebaceous glands in the skin) |
1) fatty acid (oily protective barrier 2) antibacterial, antifungal 3) lower skin pH 4) most microorganisms grow best at neutral pH |
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What do goblet cells do? |
secrete mucous and trap microbes |
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What are ciliary escalators? |
ciliated epithelial cells in trachea and nasopharynx -cilia push bacterial cells back up, they get trapped in mucous and coughed out of swallowed (then killed by stomach acid) |
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How does normal flora help to prevent infection? |
-microbial antagonism: normal flora inhibits colonization by pathogenetic microorganisms through: -normal flora educates our adaptive immune responseW |
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Define the immune system |
the cells, tissues and molecules that mediate resistance to infection |
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What do microbial flora do? |
inhibit pathogen invasion by occupying GI space and thereby preventing pathogens from colonizing the host |