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16 Cards in this Set
- Front
- Back
What is pharmacodynamics (PD)?
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-The action of drugs on the body
-Involves: receptor binding, post-receptor effect, and chemical interaction |
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What is Pharmacokinetics (PK)?
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-Actions of the body on a drug
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For PK, what does ADME stand for?
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-A: Absorption
-D: Distribution -M: Metabolism -E: Excretion |
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What are excipients?
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Inactive substances used as a carrier for the active ingredient (drug substance)
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What is an orphan drug?
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A drug that targets a rare disease affecting fewer than 200,000 people.
-Rarely made due to cost/benefits |
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How does the DEA organize controlled substances?
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-5 Schedules, 1 is most addictive with the highest dependence potential (ex. 1 = Heroine, Pot) (5 = Codine, cough preps)
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Which schedule has no medical uses?
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Schedule 1 (LSD, Heroine)
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Example of a Schedule 2?
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Morphine, Amphetamine
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Example of a Schedule 3?
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Ketamine, thiopental, anabolic steroids
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Example of a Schedule 4?
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Ambien
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Example of a schedule 5?
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Codine, cough preps
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What words can drugs use but supplements cant?
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-Protects
-Lowers -Reduces -Prevents |
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What is
phase 1 of a clinical trial? |
-Safety (among small group of HEALTHY individuals)
-Pharmokinetics (dose range) (single/multiple/food effect) |
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What is phase 2 of a clinical trial?
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-Safety (among larger group of patients with DISEASE or condition)
-Efficacy (optimal dose/schedules) |
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What is phase 3 of a clinical trial?
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-PROVE Safety (Long! 3 yrs, Thousands of patients)
-PROVE Efficacy |
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What is phase 3 of a clinical trial?
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-Post-Marketing Studies
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