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19 Cards in this Set
- Front
- Back
What are the ssx of vitiligo? |
1. Asymptomatic, flat, well-demarcated
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What are the MCC of vitiligo? |
1. Pernicious anemia 2. Addison's 3. Hashimoto |
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What are ephelides? |
1. Freckles |
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What are the ssx of lentigo? |
1. Benign localized hyperplasia of melanocytes 2. DO NOT darken when exposed to sunlight |
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1. Lentigo simplex histology 2. Hyperpigmented rete ridges |
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1. Solar lentigo histology 2. Hyperpigmented rete ridges 3. Solar elastosis |
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1. Labial lentigo 2. Basal layer hyperpigmentation 3. Broad rete ridges |
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1. Junctional nevus |
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Compound nevus |
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Intradermal nevus |
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Dysplastic nevus |
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What are the risk factors for melanoma? |
1. Fair skin 2. FHx 3. Exposure to carcinogens 4. Presence of multiple birthmarks |
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What are the signs of a malignant melanoma? |
1. Asymmetric 2. Borders uneven 3. Two or more colors 4. Larger than 1/4 inch 5. Changes in size, color, or other trait |
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What occurs in the radial growth phase of melanoma? |
1. Horizontal spread within epidermis to superficial dermis 2. Lack capacity to metastasize |
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What is lentigo maligna? |
1. Indolent lesion on face 2. May remain in radial growth phase for several decades |
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What is the superficial spreading class of melanoma? |
1. Most common type 2. Involves sun-exposed skin |
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What is the acral/lentiginous melanoma class of melanoma? |
1. Unrelated to sun exposure |
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What is the vertical growth phase of melanoma? |
1. Tumor cells invade downward into deeper dermal layers 2. Appearance of nodule 3. Maturation is absent from deep invasive portion of melanoma |
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What are the prognostic factors for melanoma? |
1. Depth (Breslow thickness) 2. number of mitoses 3. Tumor regression 4. Number of tumor-infiltrating lymphocytes 5. Gender (female is better) 6. Location |