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31 Cards in this Set

  • Front
  • Back

Father of Genetics

Gregor Johann Mendel (1822-1884)

Factor

Inherited unit which were named byMendel and are called genes now

Allele
alternative form of a gene

Crossing -Over

Exchange of Genetic material between the non-sister chromatids of a homologous chromosomes

Cistron

Functional unit of DNA

Recon

Unit of Recombination

Muton

Unit of Mutation

Phenotype

This is the "outward, physical manifestation" of the organism.

Genotype

This is the "internally coded, inheritable information" carried by all living organisms. This stored information is used as a "blueprint" or set of instructions for building and maintaining a living creature.
Wildtype
This is known as the standard to which all other mutations are compared

Hetrozygous

Two different Alleles of genes

Homologous

Two copies of genes are identical

Multiple allele

Involves more than just the typical two alleles that usually code for a certain characteristic in a species.




There is more than two phenotypes available


eg ABO Blood group system

Pseudoalleles

Functionally related and Closley linked genes

Back Cross

Cross between F 1 and one of the Parent

Test Cross

Cross between F 1 and Recessive Parent

Complementation Test OR Cis Trans Test

Determines two mutations in same gene or Different




Cis - same Homology


Trans - On Separate Homology




eg - sex linked genes for eye color in Drasophila

Threshold effect
normal phenotypic expression occurs anytime a certain level of gene product is attained

Incomplete Dominance

When neither of alleles are dominant

Supplementary gene interaction

second dominant genes express itself when supplemented by other dominant gene of a pair

Epistasis

Masking effect of one dominant gene by other


eg Fruit color in squash

Polymerism OR Additive Factor

When Dominant form of both genes are present , then it produces double effect


Eg Color of Wheat

Duplicate factor

Ressisive forms when together produce different Phenotype


Eg Awned and Awneless rice

Inhibitory factor

One dominance gene inhibits or suppress expression of dominant gene


eg Plumage color in Poultry

Pleiotropy

It is the Phenomenon in which one gene affects multiple , apparently ,unrelated , Phenotypes

Genomic Imprinting

Differential inheritance of genetic material from the mother versus the Father


Eg : Prader- Willi Syndrome, Anglemam Syndrome

Penetrance

Percentage of individuals with given genotypes who exhibits the phenotype associated with that genotype

Expressivity

Measures the extent to which a genotype is expressed at phenotypic level

Variable Expressivity
When a trait is not manifested uniformly among the individuals that show it.



Example : Drosophila's Lobe mutation- Dominant mutation- Phenotype is extremely variable

Phenocopy

Term given to individuals whose Phenotype under a particular environmental condition becomes identical to one of another individual whose phenotype is determined by genotype

Genetic anticipating
Increase of expression through generations