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What can happen when adherence to certain receptors on the phagocyte's surface
Respiratory burst:
activation of NADPH oxidase
production of superoxide radical
superoxide converted to peroxide by superoxidase dismutase
Oxygen-dependent killing

Oxygen-independent killing
For gram +

gram -
Evasion by:
1. Thick peptidoglycan
2. Cover with capsule
3. MAC (membrane attack complex) at arm's length
4. Sialic acid which induces avoidance
5. enzymes that degrade C3b
Evasion of complement
Inhibition of chemotaxis via
1. cord factor: inhibits PMN migration

2. elastase: inactivates C5a

3. C5a peptidase: degrades C5a
Inhibition of phagocytosis via
Capsule
Porins
M protein which blocks binding of C3b
Protein A