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108 Cards in this Set

  • Front
  • Back
Heart Failure
(HF)
--Abnormal condition involving impaired cardiac pumping
--HF (aka CHF) is not a disease but a “syndrome”
Associated with long-standing HTN & CAD
--Results from the heart’s inability to pump amt of oxygenated blood needed to meet metabolic requirements of body
Statistics
(HF)
--Affects about 5.7 million people (AHA,2012)
--Most common reason for hospitalization in adults older than 65
--About ½ of all people who have heart failure die within 5 years
--Heart Failure costs the nation $34.4 billion each year
Incidence hasn’t ↓ in 2 decades but overall survival ↑
Risk Factors
(HF)
--Age
--Hypertension
----To compensate for ↑ B/P the heart muscle thickens
----Over time force of heart muscle contraction weakens preventing normal filling of heart with blood
--High cholesterol
--African American descent
----Related to the higher incidence of HTN & DM
----Have a 30% higher mortality rate
Etiology & Pathophysiology
(HF)
--May be caused by an interference with normal mechanisms regulating cardiac output (CO)
----CO = HR X SV (amt of blood pumped from LV with each contraction)

CO influenced by:
--Preload = Volume of blood in ventricle at end of diastole
--Afterload =
--May be caused by an interference with normal mechanisms regulating cardiac output (CO)
----CO = HR X SV (amt of blood pumped from LV with each contraction)

CO influenced by:
--Preload = Volume of blood in ventricle at end of diastole
--Afterload = Force ventricle must develop to eject blood into circulatory system
--Myocardial contractility
--Heart rate
--Metabolic state of individual
Types of HF
Left-sided failure
--Most common form
--Blood backs up through left atrium into pulmonary veins
--Pulmonary congestion & edema

Right-sided failure
--Backflow to right atrium & venous circulation
--Results from diseased right ventricle
--One-sided
Left-sided failure
--Most common form
--Blood backs up through left atrium into pulmonary veins
--Pulmonary congestion & edema

Right-sided failure
--Backflow to right atrium & venous circulation
--Results from diseased right ventricle
--One-sided failure eventually leads to biventricular failure
Left-Sided Heart Failure
Right-Sided Heart Failure
Clinical Manifestations
(acute HF /CHF)
Pulmonary edema
--Agitation
--Pale or cyanotic
--Cold, clammy skin
--Severe dyspnea, crackles, cough (hacking, productive, dry), “frothy” secretions
--Tachypnea
--Tachycardia

Signs & symptoms of low cardiac output:
--Think “head-to-toe” assessment & abnormal heart sounds (e.g. S3, S4, murmur)

Fatigue
--Earliest symptoms, after activities which are normally not tiring
----Related to decreased CO

Dyspnea (PND) or SOB
--Cause by alveolar edema
--PND – reabsorption from dependent areas when patient is sleeping
--Pt c/o suffocation feelings

Tachycardia
--Compensatory mechanism from SNS

Heart murmur, S3, S4

Heaves/Lift
--3rd to 5th intercostal spaces using ball of your hand

Edema/Anasarca
--Legs, liver, abdomen

Nocturia
--Related to recumbent position ↑ renal blood flow

Chest pain
--Related to decreased coronary perfusion from ↓ CO & ↑ work of heart
--Can be anginal pain

Weight changes
--Multifactoral

Skin changes
--Dusky appearance

Many patients suffer from sleep obstructive apnea

Behavioral changes
--Restlessness, confusion, ↓ attention span, some (impaired cognition), sleepiness
Complications
(HF)
--Pleural effusion
--Arrhythmias
--Left ventricular thrombus
--Hepatomegaly
--Pulmonary hypertension
Symptom Classification System
(HF)
I -  No symptom limitation with ordinary physical
activity

II - Ordinary physical activity somewhat limited  by
dyspnea (ie, long distance walking,  climbing 2
flights of stairs)

III - Exercise limited by dyspnea at mild work  loads
(ie, short distance walking, climbing  one flight of
stairs)

IV - Dyspnea at rest or with very little exertion
Classification of Chronic Heart Failure
A
 - High risk for developing heart failure
--Hypertension, diabetes mellitus, CAD, family history of cardiomyopathy

B
 - Asymptomatic heart failure
--Previous MI, LV dysfunction, valvular heart disease

C - 
Symptomatic heart failure
--Structural heart disease, dyspnea and fatigue, impaired exercise tolerance

D - 
Refractory end-stage heart failure
--Marked symptoms at rest despite maximal medical therapy
Diagnostics
(HF)
--Primary goal to determine underlying cause
--History & physical exam
--ABGs, serum chemistries
--Chest X ray
--12-Lead ECG
--Hemodynamic assessment/monitoring
--Echocardiogram (determines LVEF)
--Stress testing
--Nuclear imaging studies
--Cardiac catheterization
--Laboratory tests; CBC, BMP, HBA1C, Lipid profile, thyroid levels, cardiac enzymes and B type natriuretic peptide level (BNP)
Nursing & Collaborative Management
(AHF)
Primary goal is to improve LV function by:
↓ intravascular volume
↓ preload (venous return)
↓ afterload
Improving gas exchange & oxygenation
Improving cardiac function
Reducing anxiety
HCP Orders
(AHF)
--Oxygen 2L/min via nasal cannula
--Lasix 40 mg IV push STAT and every 12 hours
--Insert peripheral IV D5W at 5 ml/hr
--Insert Foley catheter
In-Depth Nursing & Collaborative Management
(AHF)
1. ↓ preload
--Reduce the amount of volume returned to the LV
--Diuretics
--Nutritional therapy
--High Fowler’s position

2. ↓ afterload
--↓ pulmonary congestion
--ACE inhibitors/ARBs
--Nesiritide (Natrecor) – both afterload & preload reducer

3. Improving gas exchange & oxygenation
--↓ pulmonary congestion
--IV Morphine
--Administer oxygen
--Possible intubation

4. Improving cardiac function
--Digoxin (Lanoxin) (enhance contractility)
--Newer inotropics
--e.g., PDE III inhibitor: Milrinone (Primacor)
--Beta-blockers
--Hemodynamic monitoring

5. ↓ anxiety
Nursing & Collaborative Management
(Chronic HF)
--Treat underlying cause
--Maximize (optimize) cardiac output
--Alleviate symptoms
--Rest
--Biventricular pacing (Generic: Cardiac Resynchronization Therapy or CRT)
--Oxygen treatment
--Mechanical hearts
--Heart transplantation
Drug Therapy
(Chronic HF)
--ACE Inhibitors
--Angiotensin-II Receptor Blockers (ARB)
--Inotropic drugs
--Digoxin
--PDE III inhibitor
--Vasodilators
--Beta Blockers
--Diuretics
--Anticoagulants (e.g.,Warfarin)
--Antidysrhythmic drugs
Nutrition Therapy
(Chronic HF)
Fluid restrictions not commonly prescribed

Sodium restriction
--1.5 gm sodium diet (AHA 2010)

Daily weights
--Same time each day
--Wearing same type of clothing

Teach patients on how to read food labels
Discharge Teaching
(Chronic HF)
MAWDS
--Medications
--Activity
--Weight
--Diet
--Symptoms

Follow-up Appointment
Nursing Management
(chronic HF)
Nursing ASSESSMENT
--Past health history
--Medications
--Functional health problems
--Objective sx: cold, diaphoretic skin, tachypnea, tachycardia, crackles, abdominal distention/pain (feel bloated), restlessness
--(See detailed list of sx, Chapter 34)

Nursing DIAGNOSES
--Activity intolerance (remember NYHA functional Class)
--Excess fluid volume
--Disturbed sleep pattern
--Impaired gas exchange
--Anxiety

PLANNING

Overall Goals:
--↓ peripheral edema
--↓ SOB
--↑ exercise tolerance
--Compliance with medications, diet, clinic appointments
--No complications

IMPLEMENTATION

Acute Intervention:
--Establishment of quality of life goals
--Symptom management
--Conservation of physical/emotional energy
--Support system

Ambulatory & home care:

Teaching:
--Psychological changes
--Exercise-saving behaviors
--Medications
--Diet
--Relaxation techniques
--Support groups (as needed)
--Social services referral as needed

EVALUATION
--Tissue perfusion
--Respiratory status
--Sleep
--Fluid balance
--Activity intolerance
--Anxiety control
--Knowledge: Disease process
--Support system
Healthy People 2020 Objectives
(Breast Disorders)
--↓ female deaths from breast cancer
--↑ proportion women who receive a breast cancer screening based on most recent guidelines
--↓ deaths from prostate cancer
--↑ proportion of men who have discussed with their HCP whether or not to have a prostate-specific antigen (PSA) test to screen for prostate cancer
Benign Breast Disorders
Fibroadenoma

Fibrocystic Breast Changes
Fibroadenoma
(Benign Breast Disorders)
Solid, slowly enlarging, benign mass; round, firm, easily movable, nontender, and clearly delineated from surrounding tissue

Usually located in upper outer quadrant of breast
Fibrocystic Breast Condition
(Benign Breast Disorders)
--Fibrocystic changes of breast (may involve lobules, ducts, stromal tissues)
--Common in premenopausal women between 20 and 50 years of age
--Possibly caused by imbalance in normal estrogen-to-progesterone ratio
--Rubbery, ill-defined
--Painful/Tender
--Increased tenderness & size prior to menstruation
--Symptoms increase in the *premenstrual phase*
Collaborative Care
(Fibrocystic Breast Changes)
Diagnostic studies:
--Aspiration or needle biopsy
--Mammography or ultrasound

--Surgical removal
--Supportive undergarments
--OTC pain relievers
--Caffeine
--Vitamins
--Low Na+ diet or diuretics
--Hormones
Breast Cancer
Types

Complications:
--Invasion of lymph channels causing skin edema
--Metastasis to lymph nodes
--Bone, lungs, brain, liver—sites of metastatic disease from breast cancer
--Ulceration of overlying skin
Clinical Manifestations
(Breast Cancer)
--Single lump, mass, or mammographic abnormality
--Painless, hard, irregular edges > likely to be cancerous
--Can also be tender, soft or rounded
--Orange peel appearance
--Swelling of all or part of a breast
--Skin irritation or dimpling
--Breast o
--Single lump, mass, or mammographic abnormality
--Painless, hard, irregular edges > likely to be cancerous
--Can also be tender, soft or rounded
--Orange peel appearance
--Swelling of all or part of a breast
--Skin irritation or dimpling
--Breast or nipple pain
--Nipple retraction (turning inward)
--Redness, scaliness, or thickening of nipple or breast skin
--A discharge other than breast milk, e.g., clear or bloody
Men
(Breast Cancer)
--Of all breast cancers, only 1% occur in men
--Usually presents as hard, painless, subareolar mass
--Often widely spread disease because it is usually detected at a later stage than in women
Screening
(Breast Cancer)
--American Cancer Society Guidelines for the Early Detection of Cancer
--The American Cancer Society recommends these screening guidelines for most adults.

Breast cancer
--Yearly mammograms are recommended starting at age 40 and continuing for as long as a woman is in good health
--Clinical breast exam (CBE) about every 3 years for women in their 20s and 30s and every year for women 40 and over
--Women should know how their breasts normally look and feel and report any breast change promptly to their health care provider. Breast self-exam (BSE) is an option for women starting in their 20s.
Screening: The United States Preventative Service Task Force (USPSTF)
(Breast Cancer)
--The USPSTF recommends biennial screening mammography for women aged 50 to 74 years.
--The decision to start regular, biennial screening mammography before the age of 50 years should be an individual one and take patient context into account, including the patient's values regarding specific benefits and harms.
--The USPSTF concludes that the current evidence is insufficient to assess the additional benefits and harms of screening mammography in women 75 years or older.
--The USPSTF recommends against teaching breast self-examination (BSE).
--The USPSTF concludes that the current evidence is insufficient to assess the additional benefits and harms of clinical breast examination (CBE) beyond screening mammography in women 40 years or older.
Diagnostics
(Breast Cancer)
--Same as fibrocystic breast disease
--Ploidy status
----Tumor differentiation (abnormality)
----Correlates with tumor aggressiveness
--Axillary Lymph Node vs. Sentinel Lymph Node Dissection
--Tumor size: Larger the tumor, the poorer the prognosis
--Stages: TNM classification
Surgical Therapy
(Breast Cancer)
Lumpectomy
--Conserves the breast, nipple
--Removal of tumor with small amts of normal tissue
--Radiation post removal
--ALND vs. SLND

Modified radical mastectomy
--Removal of breast & axillary nodes but conserves the pectoralis muscle
Radiation Therapy
(Breast Cancer)
--Radiation Therapy (Breast Cancer)
--Primary treatment (5-6 weeks)
--Shrink a large tumor size to operable size
--Palliative treatment for pain
--Brachytherapy
Chemotherapy (Breast Cancer)
--Cytotoxic drugs to destroy cancer cells
--Administered pre- & post-op
--Pre-op (neoadjuvant): Shrink tumor, < extensive surgery
--Suppresses tumor growth & prolongs survival
Prophylactic Oophorectomy
(Breast Cancer)
If BRCA gene mutation
Hormonal Therapy (Breast Cancer)
--Tamoxifen Citrate (Novaldex) – blocks estrogen
--Post-menopausal women w/out lymph node involvement, BRCA 2 mutation, or ↑ risk breast cancer
--Prevention in individuals in high risk category
--Side effects: Hot flashes, nausea, vomiting, blood clots, & endometrial cancer
Post Op Nursing: Surgical Management
(Breast Cancer)
--LOC, V/S
--Bleeding (dsg, drains)
--Infection
--Avoid BP, injections, phlebotomy affected arm
--Ambulation & diet
--Postmastectomy exercises
--Breast reconstruction
--Adjuvant therapy
--LOC, V/S
--Bleeding (dsg, drains)
--Infection
--Avoid BP, injections, phlebotomy affected arm
--Ambulation & diet
--Postmastectomy exercises
--Breast reconstruction
--Adjuvant therapy
Discharge Teaching
(Breast Cancer)
--Psychosocial
--Infection
--Incisional & drain care
--Exercises
--Lymphedema
--Health promotion
--Follow up care
--Sexuality
Benign Prostatic Hyperplasia (BPH)
Glandular units in the prostate that undergo an increase in number of cells, resulting in enlargement of prostate gland
Glandular units in the prostate that undergo an increase in number of cells, resulting in enlargement of prostate gland
Symptoms
(BPH)
--Hyperirritable bladder
--Urgency and frequency
--Hypertrophied bladder wall muscles
--Cellules and diverticula
--Hydroureter
--Hydronephrosis
--Overflow urinary incontinence
Potential Complications
(BPH)
Surgical Procedures
(BPH)
Transurethral resection of prostate (TURP)

Prostatectomy
--Suprapubic
--Retropubic
--Perineal
Transurethral resection of prostate (TURP)

Prostatectomy
--Suprapubic
--Retropubic
--Perineal
Postoperative Care
(Prostatectomy Procedures, BPH)
Urinary catheter with retention balloon placed into bladder

Traction via taping to patient’s abdomen or thigh

Uncomfortable urge to void continuously
Diagnostics
(BPH)
--Digital rectal exam
--Urine analysis and culture
--Serum creatinine and BUN
--PSA (Prostate Specific Antigen)
--Urodynamic flow studies
--Cystourethroscopy
Treatment Goals
(BPH)
Restore bladder drainage

Relieve symptoms

Treat complications
Drug Therapy
(BPH)
Hormonal manipulation (androgen)
--Proscar

Alpha-adrenergic blockers
--Minipress, Cardura, Hytrin
--Side effects: orthostatic hypotension, dizziness
Conservative Therapy
(BPH)
Stents, prostatic balloon

Foley catheters
Invasive Therapy
(BPH)
TURP

Indications:
--Decrease in urine flow sufficient to cause discomfort
--Persistent residual in urine
--Acute urinary retention
--Hydronephrosis

Transurethral Resection of Prostrate (TURP)
--Choice for debilitating patient with moderate pros
TURP

Indications:
--Decrease in urine flow sufficient to cause discomfort
--Persistent residual in urine
--Acute urinary retention
--Hydronephrosis

Transurethral Resection of Prostrate (TURP)
--Choice for debilitating patient with moderate prostatic enlargement
--No incision, less likely to cause erectile dysfunction
--Does not completely remove the prostate tissue
--Bleeding is common (What medications to check pre-op?)
Pre-operative: Assessment/Nursing Diagnoses
(TURP)
--Pre-operative: Assessment/Nursing Diagnoses (TURP)
--Pain (? Anxiety)
--Fear related to sexual dysfunction
--Possible diagnosis of cancer
--Knowledge deficit (surgery)
--Risk of infection
Pre-operative Nursing Interventions
(TURP)
--Urethral catheter – to restore urinary drainage
--Coude catheter (curved tip catheter)
--Filiform (rigid)
--Treat urinary infection
--High fluid intake (2-3 L/day)
Post-operative: Assessment/Nursing Diagnoses
(TURP)
--Pain related to bladder spasms
--Urge incontinence related to poor sphincter control
--Potential for hemorrhage
--Hyponatremia
Post-operative Nursing Interventions
(TURP)
--CBI: Use of 3 way foley catheter; removes clots, urinary drainage
--Observe for hemorrhage
--24-36 hours, normal blood clots
--Avoid activities that increase intra-abdominal pressure
--Relieve bladder spasms
--Belladonna, opium, suppositories, antispasmodics
--Promote sphincter tone
--Kegel’s exercise
--Monitor for signs and symptoms of infection
--Dietary interventions, stool softeners
Patient Teaching
(TURP)
--Catheter care
--Managing incontinence
--Maintain adequate oral intake (2-3 L/day)
--Sexual counseling
----Erectile dysfunction
----Retrograde ejaculation
Prostate Cancer
--Malignant tumor of the prostate gland
--Most common form of cancer in men (1 in 5 men)
----Lifetime risk 15.9% (Howlader et al., 2011)
--2nd leading cause of cancer death in men after lung cancer
--Higher incidence in men > 65 years & majority of deaths after age 75
--High risk: African American men
--Research: Possible link to high-fat diet & environmental factors
--Androgen-dependent adenocarcinoma
----Slow growing & usually begins in the posterior or lateral portions of the prostate
----Spread to pelvic bones, femur (bones), lymph, lower spine, liver and lungs
Clinical Manifestations
(Prostate Cancer)
Asymptomatic in early stage

Symptoms are similar to BPH
--Dysuria, dribbling, frequency, hematuria, nocturia and retention
--Prostate feels hard, enlarged, and fixed on rectal exam
--Pain in the lumbosacral area with radiation down the hips and legs are indicative of metastasis (? Renal calculi symptoms)
--Distant metastasis & pain management issues
Diagnostic Studies
(Prostate Cancer)
Digital rectal exam
--Abnormal findings on rectal examination include areas of firmness, either localized (nodules) or generalized. Bogginess and asymmetry may also be noted.

(+) elevated prostate-specific antigen (PSA)
--Normal (0.2 – 4 ng/mL)
--Mild elevation with other disorders, e.g. BPH, UTI
-- > PSA » >tumor mass

Trans-rectal ultrasound

Prostate biopsy – confirms diagnosis

CT or MRI to assess metastasis

*Elevated alkaline phosphatase* indicates bone metastasis

Grading & Staging (TNM classification)
Surgical Options
(Prostate Cancer)
Suprapubic Prostatectomy:
--Pt has co-existing problems
--Suprapubic catheter & Foley catheter is inserted
----Foley catheter is removed 2-4th postoperative day
----Suprapubic tube has a greater risk for bladder spasms
----Monitor frequently for urin
Suprapubic Prostatectomy:
--Pt has co-existing problems
--Suprapubic catheter & Foley catheter is inserted
----Foley catheter is removed 2-4th postoperative day
----Suprapubic tube has a greater risk for bladder spasms
----Monitor frequently for urine on dressing
--Post-op CBI
----Watch for hyponatremia & seizures

Retropubic Prostatectom:
--No bladder incision
--Catheter care
----Clean urethral meatus with soap and water
----Secure catheter
--Wound serosanguinous for 4-5 days
--Discharge with catheter for 3-5 days
--Urinary incontinence – Kegel’s exercises
--Discharge Teaching:
----No lifting heavy objects, no driving, no sex, drink 2-3 liters/day, stool softeners, high fiber in diet, walk, question about impotence
Erectile Dysfunction
Inability to achieve or maintain erection for sexual intercourse

Organic vs. functional ED

Assessment:
--Medical, social, sexual history
--Complete physical examination
--Duplex Doppler ultrasonography test
Healthy People 2020
(Cancer)
↓ overall cancer rate

↑ proportion of cancer survivors living 5 yrs or > after dx

↑ mental & physical health-related quality of life of cancer survivors
Urinary Tract Infection (UTI)
Most common health care acquired infection

Most common cause of sepsis in hospitalized patient
--“Urosepsis”
--Most common organisms are from GI tract
--E. coli (most common)
--Common source of hospital-acquired UTI (CAUTI)
Classification
(UTI)
Upper tract: renal parenchyma, pelvis, ureters
--Signs and symptoms: fever, chills, flank pain

Lower tract: lower urinary tract
--No usual systemic manifestations (localized symptoms)

Sites of Infection
--Pyelonephritis
--Cystitis
--Urethritis
Predisposing Factors
(UTI)
Factors increasing urinary stasis
--Intrinsic obstruction, extrinsic obstruction, urinary retention

Foreign bodies
--Urinary calculi, urologic instrumentation (CAUTI)

Anatomical factors
--Congenital defects leading to obstruction or urinary stasis, fistula exposing urinary stream to skin, vagina, or fecal stream, shorter urethra

Sexual intercourse

Immunosuppression

Functional disorders (constipation, voiding dysfunction)
Clinical Manifestations
(UTI)
Symptoms
--Dysuria, frequent urination (> every 2 hours), urgency, suprapubic discomfort or pressure
--Hematuria, or sediment in urine, cloudy urine
--Flank pain, chills, and fever indicate pyelonephritis

Older adult:
--Could be asymptomatic
--Non-localized abdominal discomfort rather than dysuria
--May have cognitive impairment
--Less likely to have fever

Significant bacteriuria may have no symptoms or nonspecific symptoms like fatigue or anorexia
Diagnostics
(UTI)
Urinalysis (clean-catch is preferred, or catheterization or suprapubic needle aspiration)

Urine culture and sensitivity

Imaging studies in some cases
--IVP or abdominal CT when obstruction suspected
Drug Therapy
(UTI)
Trimethoprim-sulfamethoxazole or nitrofurantoin
--Used to treat empiric uncomplicated UTI )

Pyridium
--OTC, provides soothing effect on urinary tract mucosa
--Stains urine reddish orange

Prophylactic or suppressive antibiotics
--Patients with repeated UTIs
--Prevent recurrence, or a single dose prior to events likely to cause UTI
Health Promotion
(UTI)
--Avoid unnecessary catheterization & early removal of indwelling catheters
--Aseptic technique must be followed during instrumentation procedures
--Handwashing
--Wear gloves for care of urinary system
--Routine & thorough perineal care for all hospitalized patients
--Avoid incontinent episodes by answering call light & offering bedpan at frequent intervals
Acute Care Intervention
(UTI)
--Instruct patient about drug therapy & side effects
--Emphasize taking full course despite disappearance of symptoms
--Second or reduced drug may be ordered after initial course in susceptible patients
--Instruct patient to watch urine for changes in color & consistency and decrease or cessation of symptoms
--Counsel on persistence of lower tract symptoms beyond treatment or onset of flank pain or fever should be reported immediately
Ambulatory and Home Care
(UTI)
--Emphasize compliance with drug regimen
--Maintain adequate fluid intake
--Regular voiding
--Void after intercourse
--Temporary discontinue use of diaphragm
--Instruct on follow-up care with urine culture
--Recurrent symptoms typically occur in 1-2 weeks after therapy
Evaluation
(UTI)
--Use of nonanalgesic relief measures
--Appropriate use of analgesics
--Pass urine without urgency
--Urine free of blood
--Adequate intake of fluids
Glomerulonephritis
--Immunologic processes involving the urinary tract predominantly affect the renal glomerulus
--Inflammation of the renal glomeruli

Classifications:
--Extent of damage (Diffuse or focal)
--Initial cause of the disorder (SLE, scleroderma, strep infec
--Immunologic processes involving the urinary tract predominantly affect the renal glomerulus
--Inflammation of the renal glomeruli

Classifications:
--Extent of damage (Diffuse or focal)
--Initial cause of the disorder (SLE, scleroderma, strep infection)
--Extent of changes (Minimal or widespread)

--Accumulation of antigen, antibody and complement in the glomeruli, results to tissue injury
Acute Glomerulonephritis
--Patient assessment
----Connection with sore throat?
----Proteinuria
--Physical assessment
--Clinical manifestations
--Laboratory assessment
--Other diagnostic tests
Collaborative Care
(Acute Glomerulonephritis)
--Management of infection
--Prevention of complications
--Dialysis
--Plasmapheresis
--Patient education
Chronic Glomerulonephritis
Develops over period of 20 to 30 years or longer

Assessment

Interventions:
--Slowing progression, preventing complications
--Diet changes
--Fluid intake
--Drug therapy
--Dialysis, transplantation
Urinary Tract Calculi
Nephrolithiasis – kidney stone disease
--Majority of cases caused by calcium stones (oxalate, phosphate)
--Caucasian, 20-55 years old men

Risk factors:
--Metabolic 
--Climate 
--Urinary stasis
--Urinary retention
--Immobilization
--Dehydration
Nephrolithiasis – kidney stone disease
--Majority of cases caused by calcium stones (oxalate, phosphate)
--Caucasian, 20-55 years old men

Risk factors:
--Metabolic
--Climate
--Urinary stasis
--Urinary retention
--Immobilization
--Dehydration
--Genetic
--Lifestyle
Clinical Manifestations
(Urinary Tract Calculi)
Manifestations result from obstruction of urinary flow
--Ureterovesical junction (UVJ), common site of complete obstruction

Symptoms:
--Abdominal or flank pain (usually severe), hematuria, renal colic
--Nausea & vomiting
--Pain may be absent if stone unobstructing
--Cool, moist skin
--Stone near UVJ: lateral flank, testicles, labia, or groin
--UTI signs and symptoms, fever, vomiting, nausea and chills
Diagnostics
(Urinary Tract Calculi)
Urinalysis, urine culture, IVP, retrograde pyelogram, ultrasound, cystoscopy, CT scan

Serum BUN, creatinine

H & P: Use of OTC medications and dietary supplements, previous history, family history
Endourologic, Lithothripsy or Open Surgical Stone Removal (Nephro or Pyelolithotomy)
(Urinary Tract Calculi)
Indications:
--Stones are too large for spontaneous passage
--Stones associated with bacteriuria or symptomatic infection
--Stones causing impaired renal function
--Stones causing persistent pain, nausea, or ileus
--Inability of patient to be treated medically
--Patient with one kidney
Nursing Management
(Urinary Tract Calculi)
Assessment
--Clinical manifestations
--Subjective and objective data

Nursing Diagnoses
--Acute pain/Anxiety
--Impaired urinary elimination
--Ineffective therapeutic regimen management
--Risk for infection

Goals
--Relief of pain
--No urinary tract obstruction
--Understanding of measures to prevent further recurrence of stones

Implementation
--Adequate fluid intake (goal: 2 L/day UO)
--Measures to alleviate risk factors
--Fluid intake should be advised according to persons’ activity, underlying illness, etc
--Normal Ca++ diet, low animal protein, salt or both
--Pain management & comfort measures
--Teach patient to report spontaneous passage of stone
--Encourage mobility
--Safety measures, for patients experiencing acute colic, particularly if using opioid analgesics
--Ice packs for bruising with lithotripsy
Bladder Cancer
--Most frequent malignant tumor of the urinary tract is transitional cell carcinoma of the bladder
--Most common in men, between 60-70 years

Risk factors:
--Cigarette smoking
--Exposure to dyes used in rubber and cable industries
--Chronic abuse of certain analgesics (phenacetin)
--Women treated with radiation for cervical cancer
--Cylophosphamide (Cytoxan), unknown mechanism
--Chronic recurrent bladder stones and chronic lower urinary tract infections
--Chronic indwelling catheters (long periods)
Clinical Manifestations & Diagnostics
(Bladder Cancer)
--Gross painless hematuria (common finding)
--Bladder irritability with dysuria, frequency, and urgency

Diagnostic studies:
--Urine for cytology
--Detects exfoliated cells from the bladder
--IVP, ultrasound, CT or MRI
--Cystoscopy- biopsy confirms diagnosis
--TNM staging
--Low-stage, low-grade bladder cancers are most responsive to treatments and more easily cured
Nursing & Collaborative Care
(Bladder Cancer)
--Prepare patient for diagnostic procedures
--History and Physical exam
--Pre and post-op care
--Surgical therapy
----Transurethral resection
----Laser photocoagulation
----Open loop resection
----Cystectomy
----Segmental
----Partial
----Radical
--Radiation and Chemotherapy
--Intravesical therapy
----Immunotherapy
----Chemotherapy
Urinary Diversion
(Bladder Cancer)
Performed with & without cystectomy

Indications:
--Cancer of the bladder
--Neurogenic bladder
--Congenital anomalies
--Strictures
--Trauma to the bladder
--Chronic infections with deterioration of renal function

Types of urinary diversion surgery requiring collection devices
--Ileal conduit
--Cutaneous ureterostomy
--Nephrostomy
Incontinent Urinary Diversion
(Bladder Cancer)
--Ileal conduit (ileal loop), most common type: 6-8 inches of ileum are converted into a conduit for urinary diversion
--Ureters are anastomosed into one end of the conduit, and other end of the bowel is brought out to the abdominal wall to form a stoma
--Ileal conduit (ileal loop), most common type: 6-8 inches of ileum are converted into a conduit for urinary diversion
--Ureters are anastomosed into one end of the conduit, and other end of the bowel is brought out to the abdominal wall to form a stoma
--Urine flows continuously
--Requiring external collection device, requires frequent emptying
--Risk for infection

Teaching
--Care of stoma & appliance
--Increase fluid intake
--Signs and symptoms of infection
Continent Urinary Diversion
(Bladder Cancer)
--Intra-abdominal reservoir that is catheterizable or has an outlet controlled by anal sphincter
--Internal pouches created similar to ileal conduit
--Reservoirs from ileum, ileocecal segment or colon, e.g., Kock pouch
--Continence mechanism formed bet
--Intra-abdominal reservoir that is catheterizable or has an outlet controlled by anal sphincter
--Internal pouches created similar to ileal conduit
--Reservoirs from ileum, ileocecal segment or colon, e.g., Kock pouch
--Continence mechanism formed between large, low pressure reservoir and the stoma by intussuscepting a portion of the bowel

Patient Teaching
--Self catheterization using strict sterile aseptic technique, every
--4 to 6 hours
--No external pouch
Pre-operative: Nursing Management
(Bladder Cancer)
--Patient teaching
--Recognize anxiety level, and fear
--Patient’s family should be involved during teaching process
--Social aspects of living with stoma should be included
--Self-catheterization and irrigation of pouch
--Explain problems of incontinence
--Concerns about sexual activities should be discussed

Consult enterostomal therapy RN
Post-operative: Nursing Management
(Bladder Cancer)
Early postoperative period priorities:
--Prevention of surgical complications such as atelectasis and shock, thrombophlebitis, paralytic ileus and small bowel obstruction
--NPO
--NGT may be required for 3 to 5 days
--Prevention of injuries and maintaining urine output
--Increase fluid intake – to “flush” the continent diversion
--Explain to patient that “mucus –like” appearance in the urine is a normal occurrence

Meticulous skin care around the stoma
--Keep urine acidic to prevent alkaline encrustations
--Stoma is expected to shrink within the first few weeks postoperatively

Change appliance as needed

Psychosocial support: altered body image

Discharge planning/teaching
--Proper fitting of appliance
--Information where to purchase supplies, emergency telephone numbers, location of ostomy clubs, and follow-up visits
--Measures to prevent complications and renal function deterioration
Acute Kidney Injury (AKI)
Pathophysiology

Types:
--Prerenal
--Intrarenal
--Postrenal

Prerenal azotemia

Causes:
--Hypovolemic shock
--Heart failure
Phases of AKI
Rapid decrease in kidney function lead to collection of metabolic wastes in the body

Phases:
--Onset
--Oliguric
--Diuretic
--Recovery

Acute syndrome may be reversible with prompt intervention
Chronic Kidney Disease (CKD)
--Progressive, irreversible kidney injury; kidney function does not recover
--End-stage kidney disease (ESKD)
--Azotemia
--Uremia
--Uremic syndrome
Stages of CKD
Reduced renal reserve

Reduced GFR

ESKD
Stages of CKD Changes
Kidney changes

Metabolic changes
--Urea and creatinine

Electrolyte changes
--Sodium
--Potassium
--Acid-base imbalance
--Calcium and phosphorus

Cardiac changes:
--Hypertension
--Hyperlipidemia
--Heart failure
--Pericarditis

Hematologic changes

GI changes
Clinical Manifestations
(CKD)
--Neurologic
--Cardiovascular
--Respiratory
--Hematologic
--Gastrointestinal
--Skeletal
--Urinary
--Skin
Assessments
(CKD)
--Psychosocial
--Laboratory
--Imaging
Priority Nursing Care
(CKD)
--Dietary restrictions
--Uremic frost
--Muscle strength, energy
--Family members
--Excess fluid volume
--Decreased cardiac output
--Recombinant human erythropoietin
--Interdisciplinary team
Hemodialysis
(CKD)
--Patient selection
--Dialysis settings
--Procedure
--Anticoagulation
Subclavian Dialysis Catheters
Hemodialysis Circuit
Vascular Access
(Hemodialysis)
--Arteriovenous (AV) fistula or graft for long-term permanent access
--Hemodialysis catheter, dual or triple lumen, or AV shunt for temporary access
--Precautions

Complications:
--Thrombosis or stenosis
--Infection
--Aneurysm formation
--Ischemia
--Heart failure
Nursing Care
(Hemodialysis)
--Drugs
--Postdialysis assessment
--Hypotension
--Headache
--Nausea, vomiting
--Malaise, dizziness
--Muscle cramps or bleeding
Complications
(Hemodialysis)
--Dialysis disequilibrium syndrome
--Infectious disease
--Hepatitis B & C
--HIV
Peritoneal Dialysis
(CKD)
--Involves siliconized rubber catheter placed into abdominal cavity for infusion of dialysate

Types:
--Continuous ambulatory (CAPD)
--Automated
--Intermittent
--Continuous-cycle
--Peritoneal Dialysis Exchange
--Continuous Ambulatory Peritoneal Di
--Involves siliconized rubber catheter placed into abdominal cavity for infusion of dialysate

Types:
--Continuous ambulatory (CAPD)
--Automated
--Intermittent
--Continuous-cycle
--Peritoneal Dialysis Exchange
--Continuous Ambulatory Peritoneal Dialysis (CAPD)
Continuous Ambulatory Peritoneal Dialysis (CAPD)
(CKD)
Automated Peritoneal Dialysis
(CKD)
Complications
(Peritoneal Dialysis)
--Peritonitis
--Pain
--Exit site/tunnel infections
--Poor dialysate flow
--Dialysate leakage
--Other complications
Nursing Care
(Peritoneal Dialysis)
--Before treatment—evaluate baseline vital signs, weight, laboratory tests
--Continually monitor patient for respiratory distress, pain, discomfort
--Monitor prescribed dwell time, initiate outflow
--Observe outflow amount and pattern of fluid
Kidney Transplantation
--Candidate selection criteria
--Donors
--Preoperative care
--Immunologic studies
--Surgical team
--Operative procedure
Transplanted Kidney
Postoperative Care
(Kidney Transplant)
--Urologic management
--Assessment of hourly urine output x 48 hr

Complications:
--Rejection
--Acute tubular necrosis
--Thrombosis
--Renal artery stenosis
--Other complications
--Immunosuppressive drug therapy
--Psychosocial preparation