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132 Cards in this Set
- Front
- Back
Lichen planus has w____ S-___-
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whickam's striae
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whickham's striae is a feature of
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lichen planus
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splitting of epithelium is called
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acanthylosis
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difference betwen minor apthous ulcer and herpetiform?
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herpetiform in greater #
different mucosa MAU smaller |
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pemphigus has the protein ______
whereas pemphigoid has _____ |
pemphigus - desmoglein 3
pemphigoid lamini 5 |
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pemphigus has what protein
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desmoglein 3
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desmogelien 3 is of .....
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pemphigus
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pemphigoid has what protein?
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lamini 5
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laminin5 is of...
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pehmphigoid
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what types of VB lesions are nikolsky +?
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intraepith lesions
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which ones have tzank cells?
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herpes, pemph vulgaris
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pemph vulgairs and herpes show what kind of cells?
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tzank
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paraneoplastic pemphigus is associated with what serious condition?
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lymphoma
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darier's disease is auto....
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dominant
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dariers disease associated with what histological feature?
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corps rounds and grains
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corps rounds an grains are associated with
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darier's disease
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libman sach's endo is associated with....
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lupus
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lupus is associated with what kind of endocarditis
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libman sachs'
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what is identified by stretching and disappearing?
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leukoedema
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lesion on the side of the tounge in a HIV/EBV patient?
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hairy leukoplakia
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erythema multiforme
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white sponge nevus
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actinic solar cheilitis
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desquamative gingivitis seen with....
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pemphigus
cicatricial pemphigoid chroniculcerative stomatitis |
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angular cheilitis
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fordyce granules
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what is it?
what kind of base? what else could it be? what is its cause? |
nodule
sessile base fibroma trauma |
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inflammatory papillary hyperplasia
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what is it?
what is the characteristic on top the lesion? |
basal cell carcinoma
telangiectasia |
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biopsy?
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actinitc clelitis
yes |
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geographic tongue
no tx |
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desquamative gingivitis
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speckled leukoplakia
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leukoedma is seen in black people ____%
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70-90%
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Hairy leukoplakia often seen with what virus
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EBV
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white sponge nevus is aut---
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dominant
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T or F
biopsy erythroplakia? |
yes
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cause of atrophic candidiasis
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ill fitting denture
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angular cheilitis
mixed infection....(3) loss of..... .....deficient |
staph/strep/candida
loss of VD vitB/iron |
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median rhomboid glossitis....85% have....
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candida
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median rhomboid glossitis
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atrophic glossitis
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T or F
atrophic glossitis can have neurologic symptoms due to pernicious aneamia |
T
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pernicious anemia is the inability to ______due to lack of____
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transfport b12 due to lack of intrinsic factor
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iron deficiency anemia
occurs due to ..... often seen w/ what syndrome? oral sign? (2) and other sign |
lack of intake or absorption
plummervinson oral - atrophic glossitis/beefy red tongue thin nails/hair |
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plummer vinson is seen with
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iron def. anemia
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what is dysphagia atrophy of upper GI?
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plummer vinson
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scarlet fever is seen with the oral sign....
treat w/.... |
strawberry tongue
treat w/ penicillin |
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hereditary hemorrhagic telangiectasia is auto...
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dominant
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clinically, hemangiomas are identified with...
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diascopy/compression
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sturge-weber syndrome is a type of _____malfromation, found in the _____area
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vascular malformation
trigeminal |
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vascular malformation found in trigeminal area
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sturge-weber syndrome
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kaposi's sarcoma is a malignancy of _____
it is due to______ |
blood vessels
loss of immuno surveillance (AIDS, lymphoma, organ trans) |
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____is a malignancy of blood vessels, due to loss of immunosurveillance (like AIDS, lymphoma, organ transplant)
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kaposi's sarcoma
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hereditary hemorrhagic telangiectasia or Osler-weber-rendu has triad of...
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cutaneous telangiectasia
recurrent epistaxis family history |
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cutaneous telangiectasia
recurrent epistaxis family history what has this triad? |
hereditary hemorrhagic telangeictasia
or osler-weber-randu syndrome |
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strawberry tongue/scarlet fever is caused by
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group a beta - hemolytic strep
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group a beta-hemolytic strep causes
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strawberry tongue
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pyogenic granulmoa is caused by....
modified by.... |
trauma modified by hormones/drugs
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pyogenic granulmoa
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peripheral gian cell granuloma
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difference between peripheral giant cell granuloma and pyogenic granuloma?
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PGCG is in anterior
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what?
cause? |
petechiae
MONO |
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hematoma is accumulation....
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of blood into tissue, produces mass
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accumulation of blood into tissue, producing a mass
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hematoma
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varix is ______
may have_____ tx_____ |
dilation of vein in lip
may have thrombosis to tx unless cosmetic concern |
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dilation of lip
may have thrombosis no tx necessary unless cosmetics concern |
varix
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small red lesion, blacnch under pressure?
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telangiectasia
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telangiectasia is a small red lesion that....
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blanches under pressure
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an extravascular lesion is one of an extravasation of blood into skin/mucosa, and ____under pressure
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does not blanch
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t or F
extravascular lesion blanches under pressure |
false
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plasma cell gingivitis is a ______, and is treatable by....
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allergic rxn
removing etiology |
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biopsy erythroplakia....
% cancer % in situ or sever dysplasia |
51 cancer
40 in situ/sev dyspl |
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etiology of atrophic lesions?
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alcohol tobacco
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erythroplakia is usually (symto/asympto)
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asympto
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treatment of erosive LP
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steroids
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leukoplakia is considere to be_____,
male predilection of _____ patients older than ____ symto/asympto dx w/_____ |
pre-malignant
males 70% older than 40 asymptomatic biopsy to dx |
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pre-malignant
males 70% older than 40 asymptomatic biopsy to dx |
leukoplakia
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which location of leukoplakia has highest risk of malignancy?
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F.O.M
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F.OM is the location of ____that has highest malignancyu
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leukoplakia
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____is due to mechanical irritation,
resembles leukoplakia and is not pre-cancerous |
firctional keratosis
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frictional keratosis is due to_____
resembles_____ and is/not precancerous |
due to mechanical irritation,
resembles leukoplakia and is not pre-cancerous |
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reticular lichen planus Is/is not symptomatic
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is not
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lichenoid rxn is a _____reaction
it is treated by.... |
allergic
stopping the causative med |
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T or F - lichenoid rxn treated by steroids
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F
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verrucuous carcinoma is ____grade, ____growing
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low, slow
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name a cancer that is low grade, slow growing
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verrucous carcinoma
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if you see ____you would suspect a pt will get AIDS in 2 years
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hairy leukoplakia
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hairy leukoplakia can be a warnign sign of
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AIDS in 2 years
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proliferative verurcous leukoplakia
more common in____ tobacco? potential for SCC? |
females
no tobacco potential for SCC |
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more common in female
not assoc w/ tobacco potential for SCC |
prolif verrucous leukoplakia
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treatment options for hyperplastic candidiasis
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Mycelex troches 10 mg-
Nystatin ointment- Nystatin oral suspension Diflucan tablets 100 mg- |
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Mycelex troches 10 mg-
Nystatin ointment- Nystatin oral suspension Diflucan tablets 100 mg- |
tx for hyperplastic candidiasis
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chronic cheilitis
___% SCC cause_____ |
10%
uv radiation |
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etiology
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HPV
a papilloma |
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pt has solitary white papillary lesion w/ sessile base
also has this on finger |
verruca vulgaris
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how to diff a papilloma vs verruva vulgaris?
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papilloma has a smaller base, vs wider base VV
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clinical feature of aspirin burn?
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whipes off
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this whiipes off
what is it? |
aspirin burn
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hand-foot-mouth is caused by
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coccaci virus
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primary HSV infection involves an intense______
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marginal ginvivitis (gingival stomatitis)
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intense marginal gingivitis (gingival stomatitis) is asign of
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primary HSV
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chronic ulcerative stomatitis tx-ed with
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anti-malarial
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anti-malarial drugs used to tx
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chronic ulcerative stomatitis
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pemphigus vs goid
intraepith? - BM? - desmoglein 3? laminin 5? |
intraepith - gus
BM - goid des 3 - goid lam5 - goid |
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markers of what? Laminin 5, BP230, BP180, collagen 7
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pemphigoid
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4 pemphigoid markers
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collagen 7
BP 230 and 180 laminin5 |
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CD 4 less than ____ = AIDS
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200
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goal of AV therapy for aids?
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reduce viral load, increase CD4
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abx prophy is necessary for HIV if...
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<500 neutrophils
<2000 WBC |
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below ___Is bad for HGB
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10
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below ___is bad Hct
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30
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below ___is dangerous for platelets
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60,000
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what is the only qual+quant test for bleeding, all the others are just
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bleeding time
quant |
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it is OK to have PT ___X the normal
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2
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pregnant people can't work on____
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CMV patients
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a patient that has kaposi sarcoma and lymphma has
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AIDS
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2 defining medical conditions with aids
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kaposi
lymphoma |
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grading cancer
1 is ____ 4 is____ |
1 - highly diff, keratin
4 - poorly diff - no keratin |
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candida is dimorphic
the form that invades tissue is the bloodstream form is |
invades - hyphal
yeast - blood |
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T or F
Hyphal form of candida is the tissue invading form |
T
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proteolytic enzyme of candida?
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SAP
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adhesin of candida?
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ALS3p
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unqique feature of ALS3p? who has this?
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candida
sticks to s. aureus |
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candida is a marker for progression of
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HIV-AIDS
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therapy for candida targets the....
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membrane
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azole works by inhibiting----
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ergosterol synthesis
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drug that works by inhibiting ergosterol synthesis
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azoles
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polyenes work by....
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incorporating into membrane, kill cell
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this drug works by incorporating into membrane of candida and kliling the cell
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polyenes
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polyene or azole
which is fungistatic? cidal? |
azole is static
polyene is cidal |
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hoiw is candida reistant?
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drug efflux pumps like ABC, CDR1/2 and MDR1
ERG11 overexpression |