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8 Cards in this Set
- Front
- Back
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Description |
Non-steroidal analgesic and antipyretic |
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Class |
non-opiod analgesia |
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Indications |
Mild to moderate pain and fever |
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Contraindications |
Hypersensitivity, previous doses within 4 hours or more than 4 grams ingested in <24 hours |
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Pharmacokinetics |
Onset: 10-60 minutes - Peak: variable - Duration: 4 hours |
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Adverse effects |
Nausea and GI irritation |
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Precaution |
Dehydration and patients with suspected liver or renal disease May be combined with codeine or other opiates in certain medications |
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Mechanism of action |
Inhibits cyclooxygenase (COX) enzymes resulting in subsequent reduction of prostaglandin signalling in the CNS to produce analgesic, antipyretic and anti-inflammatory effects |
