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7 Cards in this Set

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- Adults live in the bile duct (O.felineus have greater chance of Felines cancer and the O.viverrini cause gall bladder cancer)
- Acquired by eating fish
- This parasite is most common in southern, central and eastern Europe. Specifically, Turkey, southern parts of Russia, Vietnam and India. Also in Puerto Rico and other caribbean Islands.
- Worm causes diarrhea, thickening and eventual erosion of the bile duct wall
- Life cycle is similar to Chlonorchis
- Snail Genus Bithynia
- Fish host: cyprinid fishes
- Felines are important reservoir hosts.
Opisthorchis felineus and O.viverrini( Superfamily Opisthorchioidea)
-Tiny (1-2 mm long )flukes live in the small intestine of people
- ventral sucker is prominent (ventral sucker Gonotyl**)
- Eggs are fully embyonated but hatch in snail
-Life cycle similar
+ 1st IH freshwater and brackish water snail- Pirenella, Semisulcospira
+ 2 Rediae
+ 2nd IH fish usually Mullet or Salmon
+ Prepatent periods about 1 week
+ All larval types present in life cycle.
Heterophyids- Metagonimus yokogawai and Heterophyes heterophyes (Superfamily Opisthorchioidea)
- Distribution:
+ Middle east, Spain, Eastern Asia, Russia, Brazil
- Dh Canids, felids, people pelicans, water birds
- 2nd IH common are mullet and tilapia (they ingest fish= common host)
Heterophyes heterophyes (Superfamily Opisthorchioidea)
- Distribution:
+ Philippines, Asia, Eastern India, Ukraine
- DH dogs, cats, pelicans, other water birds and people
- 2nd IH often salmon
- A woman treated for intestinal flukes passes 55,310 worms w/in 24 hrs.
Metagonimus yokogawai (Superfamily Opisthorchioidea)
- Adults may invade or erode the mucosa and if so eggs get deposited into mucosa, they enter the lacteals and venules, and are carried to other parts of host. (small intestine )
- If light infection, no problems
- If heavy infection- bloody diarrhea, and petechial hemorrhage of submucosa (distruption of petechial hemorrphage which leads to submucosa which result in bloody diarrhea )
Metagonimus and Heterophyes (Superfamily Opisthorchioidea)
- If eggs carried to heart, vessels of heart become congested leading to heart attacks.**
- Diagnosis by fecal sedimentation and find eggs similar to Clonorchis sinensis.
- Treatment by praziquantel**
- Prevention by cooking fish in or from endemic areas and deworming the DH's
Metagonimus and Heterophyes (Superfamily Opisthorchioidea)
- In Philippines, 14% of cardiac deaths were attributed to this fluke
- In Canada a woman was found to be infected who had never been out of the country. Her infection was traced to eating SuSHi*** which had been flown in fromthe orient and was consumed in a Japanese restaurant.
Heterophyes heterophyes (Superfamily Opisthorchioidea)