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68 Cards in this Set

  • Front
  • Back

Characteristics of living systems

Metabolism- cata & ana


Responsiveness


Mvmt


Growth & differentiation


Reproduction

Levels of structural organization

Chemical


Cellular


Tissue


Organ


Organ system


Organismic

Scientific method

Observation


Hypothesis/prediction


Experimental testing


Analysis & conclusion


Develop new hypothesis

Homeostasis

Body's internal environment remains relatively constant w/ in physiological limits

Physiological limits & viability

Negative feedback

Most systems in body


Original stimulus reversed


Used for conditions that need frequent adjustment (body temp, blood sugar levels, blood pressure)

Positive feedback

Not as common


Original stimulus intensified


Seen during normal childbirth

Equilibrium

Constant state achieved w/out energy expenditure

Covalent bonds

Share electrons

Ionic bonds

Attractive force of electrical charge

Potential energy during chemical rxn

Effect of catalysts on chemical rxn

Carbs

Protein

Comprised of linear sequence of amino acids

Lipids

Nucleic acid (DNA,RNA)

Plasma membrane

Interaction surface between cell and outside world

Nucleus

Genetic material

Cytoplasm

Everything between membrane and nucleus


ICF(cytosol)


Organelles

Membranous organelles

Endoplasmic reticulum


Nucleus


Mitochondria


Golgi complex

Non membranous organelles

Cytoskeleton


Proteasomes


Ribosomes

Integral protein

Extend into/crosses cell membrane


Amphipathic

Peripheral proteins

Attached to inner or outer surface of cell membrane and are easily removed

Membrane fns

Barrier


Organization


Transport


Rxn/response

Passive transport

Down concentration gradient


No energy input


Simple diffusion,channel mediated facilitated diffusion,carrier mediated facilitated diffusion

Active transport

Against concentration gradient


Uses ATP

Diffusion

Net proportional to concentration gradient


Occurs rapidly over short distances

Simple diffusion

Hydrophobic: gasses, fatty acids, steroid hormones, fat soluble vitamins

Osmosis

Water through channels (aquaporins)

Channel mediated facilitated diffusion

Ions

Carrier mediated faciliateted diffusion

Glucose, fructose, galactose, some vitamins

Primary active transport

hydrolysis of atp chgs shape of carrier protein and pumps sub across membrane against concentration gradient

Secondary active transport

Energy stored in NA+ or H+ gradient used to move other sub against concentration gradients

Bulk transport

Endocytosis, exocytosis, transcytosis


Vesicles

Endocytosis

Vesicular transport of something into cell

Exocytosis

Vesicular transport of something out of cell

Transcytosis

Vesicular transport of something from outside of one side of cell to outside of other side of cell

Cytoskeleton

Microfilaments


Intermediate filaments


Microtubules

Microfilaments

Strands of protein (actin)


Connects organelles to membrane


Influence cell motility and shape

Intermediate filaments

Keratins


Structural stability

Microtubules

Strands of tubulin


Influence cell structure and shape


Motility- mvmt (cilia & flagella)

Centrioles/centrosomes

Cell motility/cell division

Cilia & flagella

Cell motility

Microvilli

Increase surface area of plasma membrane

Ribosomes

Site of protein synthesis

Mitochondria

Major site of cell energy metabolism

Oxidative phosphorylation

Enzyme controlled breaking of bond


Consumes O2


Produces CO2


Efficient production of ATP

Endoplasmic reticulum

Lipid&protein synthesis


Storage (protein;Ca2+)


Transport within cell


Detoxification


Rough and smooth

Rough er

Protein synthesis & storage

Smooth er

Lipid synthesis & Ca2+ storage

Golgi apparatus

Site of packaging and processing of protein products for secretion

Lysosomes

Contains digestive enzymes for recycling old cellular material

Peroxisomes

Contain enzyme for detoxification of byproducts of metabolism

Chromosomes

Nucleic acid (histones)


Made of DNA

Composition of nucleic acids

Sugar, phosphate, 1of 4 diff nitrogenous bases


Adenine


Guanine


Thymine


Cytosine

Codon

Triplet of 3 bases that rep 1 of 20 diff amino acids

Gene

Sequence of codons rep encodes (single polypeptide) protein

Chromatin

Typical condition of DNA


Dispersed DNA

Chromosomes

Cell dividing


Condensed DNA

Transcription

Synthesis of RNA from DNA


synthesis of complementary strand of RNA using base sequence of DNA as template


Occurs in nucleus


Produces mRNA


Alt splicing of exons produce distinct mRNAs from 1 gene

Translation

Synthesis of protein from RNA


Synthesis of protein using base sequence of RNA as template


Occurs in cytoplasm


Involves mRNA,rRNA,tRNA


Produces protein

Promoter

DNA sequence upstream to start of gene which RNA polymerase binds

Transcription factors

Proteins bind to promoter to augment binding of RNA polymerase

Mitosis

Prophase


Metaphase


Anaphase


Telophase

Prophase

Condensation of DNA to chromosomes

Metaphase

Alignment of chromosomes along center line or plane

Anaphase

Sep of sister chromatids to daughter cells

Telophase

Formation of 2 new nuclei