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8 Cards in this Set

  • Front
  • Back

amitriptyline / Elavil

Mech. of Action - Blocks reuptake of norepinephrine & serotonin at presynaptic membrane. Strong anticholinergic activity.




Side Effects - Dry mouth, Dizziness, Increased Appetite, Parkinsonian syndrome




Rational - Increases availability of norepi and serotonin to produce an antidepressant effect.

desipramine / Norpramin

Mech. of Action - Blocks reuptake of norepinephrine & serotonin. Strong anticholinergic activity.


Side Effects - Dry mouth, Dizziness, Blurred vision, Orthostatic hypotension, Metallic taste in mouth, EPS of fine hand tremor.


Rational - Increased availability of neurotransmitters relieves depression

doxepin / Sinequan

Mech. of Action - Increases synaptic concentrations of norepinephrine & serotonin.



Side Effects - Dry mouth, Dizziness, Blurred vision, Orthostatic hypotension, Unpleasant taste in mouth, fine hand tremor.

Rational - Produces antidepressant, anxiolytic effect

imipramine / Tofranil

Mech. of Action - Blocks reuptake of norepinephrine & serotonin.



Side Effects - Dry mouth, Fatigue, Blurred vision, Orthostatic hypotension, EPS symptoms of fine hand tremor

Rational - Relieves depression, controls nocturnal enuresis (children over 6)

maprotiline / Ludiomil

Mech. of Action - Increases synaptic concentrations of norepinephrine & serotonin.



Side Effects - Dry mouth, Dizziness, Blurred vision, Orthostatic hypotension, Unpleasant taste in mouth, fine hand tremor.

Rational - Produces antidepressant, anxiolytic effect

nortriptyline / Pamelor

Mech. of Action - Blocks reuptake of norepinephrine & serotonin at neuronal presynaptic membrane.

Side Effects - Dry mouth, Dizziness, Blurred vision, Orthostatic hypotension, Unpleasant taste in mouth, fine hand tremor.

Rational - Relieves depression, anxiety and nocturnal enuresis

trimipramine / Surmontil

Mech. of Action - Increases synaptic concentrations of norepinephrine & serotonin.



Side Effects - Dry mouth, Dizziness, Blurred vision, Orthostatic hypotension, sexual problems, fine hand tremor.

Rational - Relieves depression and anxiety

amoxaoine / Asendin

Mech. of Action - Increases synaptic concentrations of norepinephrine & serotonin.



Side Effects - Dry mouth, Dizziness, Blurred vision, Orthostatic hypotension, Unpleasant taste in mouth, fine hand tremor.

Rational - Antidepressant