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29 Cards in this Set
- Front
- Back
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First generation antipsychotics |
Conventional Antipsychotics |
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Class of Conventional Antipsychotics - Chlorpromazine (Thorazine) |
Phenothiazine |
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Class of Conventional Antipsychotics - Perphenzaine (trilafon) |
Phenothiazine |
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Class of Conventional Antipsychotics - Fluphenazine (Prolixin)* (depot) |
Phenothiazine |
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Class of Conventional Antipsychotics - Thioridazine ( Mellaril) |
Phenothiazine |
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Class of Conventional Antipsychotics - Mesoridazine (Serentil) |
Phenothiazine |
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Class of Conventional Antipsychotics - Trifluoperazine (Stelazine) |
Phenothiazine |
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Class of Conventional Antipsychotics - Thiothixene (Navane) |
Thioxanthene |
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Class of Conventional Antipsychotics - Haloperidol (Haldol) * (Depot) |
Butryophenones |
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Class of Conventional Antipsychotics - Droperidol (Inaspine) |
Butryophenones |
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Class of Conventional Antipsychotics - Loxapine (Loxitane) |
Dibenzazepine |
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Class of Conventional Antipsychotics - Molindone (Moban) |
Dihydroindolone |
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Drug Side Effects: Increased risk for metabolic syndrome and Increased salivation and sweating |
Clozapine (Clozaril) |
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Drug Side Effects: Agranulocytosis includes flu-like symptoms, sore throat, or signs of infection. Need to stop if WBC falls below 2,000/mm3 |
Clozapine (Clozaril) |
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Drug Side Effects: seizures: risk increases with dose During treatment monitoring of WBC weekly for first 6 months, then biweekly Monitor weight, blood pressure, fasting glucose and lipids, ECG |
Clozapine (Clozaril) |
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Other side effects: QT prolongation (heart rhythm) it could lead to really severe arrhythmia |
Quetiapine (Seroquel), Ziprasidone (Geodon), Aripiprazole (Abilify) (Adjunctive) |
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Higher potency, AP’s have greater risk of EPS but less sedation and anticholinergic side effects than atypical AP’s |
Conventional |
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These AP’s treat positive and negative symptoms of psychoses but have greater risk of metabolic syndrome |
Atypicals |
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Clinical response:Clinical effect seen in 30 to 60 minutes, antipsychotic action in 7-10 days, full therapeutic effect in 4 to 6 weeks. |
Conventionals |
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Clinical response: Psychotic symptoms can improve within 1 week, but it may take several weeks for full effect on behavior. Wait 4 to 6 weeks to determine efficacy. May take 4-5 months for complete response. |
Atypicals |
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Dopamine 5 HT (serotonin) Norepinephrine Acetylcholine |
Neurotransmitters involved in depression are |
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↑ the amount of available neurotransmitters either by inhibiting reuptake or inhibiting monoamine oxidase |
Antidepressants |
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Older generation agents: Tricyclics and MAO inhibitors |
Antidepressants |
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Newer generation agents: SSRI’s (Serotonin reuptake inhibitors) DNRI’s (Dopamine-norepinephrine reuptake inhibitors) SNRI’s (Serotonin –norepinephrine reuptake inhibitors) Serotonin modulatorsNorepinephrine - serotonin modulators Atypical Antidepressants |
Antidepressants |
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Takes an average of 10 to 14 days for beginning effects Full effect may not be seen for 2 to 4 weeks |
Determining an Antidepressant |
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Different people respond differently Family history of use Period of trial and error Maintenance continues until free of symptoms for 4 months to 1 year Medications slowly discontinued |
Determining an Antidepressant |
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Drug used for treatment: Immediate treatment with benztropine (Cogentin) IM (an anticholinergic) or Diphenhydramine (benadryl) IM (antihistamine) |
Acute Dystonia |
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Drug used for treatment: Amantadine (Symmetrel) oral (a dopaminergic); or Oral Cogentin (anticholinergic) |
Pseudoparkinsonism |
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Drug used for treatment: Addition of oral beta-blocker, such as propanolol (inderal). Anticholinergic such as benztropine Cognetin or Benzodiazepine diazepam (Valium) or Lorazepam (ativan) |
Akathisia |
