Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
25 Cards in this Set
- Front
- Back
what does pANCA indicate?
|
microscopic polyangitis
|
|
what drug is used to prevent uric acid stones with tumor lysis syndrome?
|
allpurinol
|
|
what do you see on microscopy with gout? +/- birefringence?
|
needle-shaped crystals with (-) birefringence
|
|
what do you see on microscopy with pseudogout? +/- birefringence?
|
rhomboid-shaped crystals with (+) birefringence
|
|
what types of substances/drugs can cause acute gouty flare-ups?
|
due to substances rich in purines, i.e. alcohol and use of thiazide diuretics
|
|
what is the main treatment for acute gout?
|
indomethicin
|
|
how does dermatomyositis present?
|
proximal muscle weakness with Gottron papules over the knuckles, heliotrope purple rash around the eyes; may also see calcifications in the subcutaneous fatty tissue
|
|
what labs are elevated with dermatomyositis?
|
elevated CK and aldolase
|
|
how do you diagnose dermatomyositis?
|
muscle biopsy
|
|
how do you treat dermatomyositis?
|
corticosteroids
|
|
what two test are highly specific for SLE?
|
anti-dsDNA and anti-Smith
|
|
vascular thrombosis + multiple miscarriages = ?? and what test may be false-positive?
|
likely anti-phospholipid syndrome, may have false-positive VDRL
|
|
how do you diagnose polyarteritis nodosa? what test is elevated in 30% of cases?
|
diagnose via tissue biopsy, pANCA is often elevated
|
|
a positive cANCA indicates what?
|
Wegner's granulomatosis
|
|
what disease is highly associated with polyarteritis nodosa you must work them up for?
|
Hepatitis B and C
|
|
patient >50 with morning stiffness of the proximal musculature with fatigue, depression and low-grade fever
|
polymyalgia rheumatica
|
|
polymyalgia rheumatica
|
treat with corticosteroids
|
|
treatment for pregnant woman with RA flare-up
|
oral prednisone
|
|
young male with chronic back stiffness, photosensitivity, oral ulcerations and fatigue
|
ankylosing spondylitis
|
|
what antigen is positive with ankylosing spondylitis?
|
HLA-B27
|
|
what diseases is HLA-B27 correlated with?
|
ankylosing spondylitis, Reiters syndrome, acute anterior uveitis, iritis, Behcet's disease, psoriatic arthritis, IBD
|
|
what is Behcet's syndrome?
|
vasculitis leading to oral ulcers, along with possible genital ulcers, skin lesions, eye inflammation
|
|
what should suspect in a patient with genital ulcers, oral ulcers and uveitis?
|
must suspect Behcet's syndrome
|
|
treatment for Behcets syndrome
|
corticosteroids
|
|
what do the T-scores indicate?
|
-1 to -2.5 = osteopenia
<-2.5 = osteoporosis |