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8 Cards in this Set
- Front
- Back
Prevention of developement of resistance in tuberculosis |
Rifampin Isoniazid Pyrazinamide Ethanbutol 2 for 4 = 4 drugs for 2 months followed by 2 drugs(isoniazid and rifampin) for 4 months |
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Isoniazid |
Isolated ranger middle lobe bullet hole = primary TB Sleeping guy = treat latent infection Mycolic acid cacti on wall Mycobacteria cowboy shot off wall = inhibits mycolic acid production Aggravating G tailed cat = Activated by catalase-peroxidase (silencing it causes to have resistance) |
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Isoniazid Side effects |
Bandit in stockings and gloves = May cause peripheral neuropathy Slow acetyl-gunslinger = Isoniazid is normally metabolized by liver N-acetyltransferase - slow acetylaters have a higher risk of side effects Pair of dice= pyridoxine (vitamin B6) excretion - addition of B6 prevents peripheral neuropathy Motion lines = may cause seizures COw liver spot = hepatotoxicity Raised LFT flag = causes asymptomatic rise in aminotransferase Lupus wolf = lupus can happen MUD PILES = anion gap metabolic acidosis Broken chrome bumper = inhibits Cytochrome P450 |
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Rifampin |
The Rifle Speeding chrome bumper = rifampin activated cytochrome P450 Shot RNA track switch = binds DNA dependant RNA polymerase Meningitis mohawk = Neisseria meningitidis H-plane = Maemophilus influenzae |
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Rifampin side effects |
Cow Liver = hepatotoxicity Puking orange = produce orange body fluids |
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Ethambutol |
Ethel the horse whisperer Arabian horse at carbohydrate wall after it knocks some of it down = blocks arabinosyl tranferase, inhibiting carbohydrate formation at the cell wall Halt! the horse = bacteriostatic |
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Ethambutol |
Red-green blinders Optic neuritis (loss of visual acuity, red-green color blindness) DEgeneration of the macula
central scotoma |
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Pyrazinamide |
The pyro knitting Needles = causes hyperuricemia and needle shaped uric acid crystal formation Yarn ball on toe = may precipitate gout attacks Cow Liver = hepatotoxicity |