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3 Cards in this Set

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  • Back

Hypothyroidism

Low free thyroxine (T4) : normal range (0.9-2.3)


High thyroid stimulating hormone (TSH): normal range (0.3-3)


Monitor TSH every 4-6 weeks until levels are normal then every 4-6 months thereafter



Drug tx: Levothyroxine


Boxed warning: use for weight loss


-decrease dose in CVD

Hyperthyroidism

FT4 is high, low TSH


Drug causes: iodine, amiodarone and interferons


Drug TX: propylthiouracil, methimazole


- inhibit synthesis of thyroid hormones


Boxed: severe liver injury and acute failure


Pregnancy : 1st trimester: PTU


2 and 3: methimazole


PTU is preferred in thyroid storm


Iodide: temporarily inhibit secretion of thyroid hormones


Ctx: hypersensitive to iodide, dermatitis herpetiforms, modular thyroid with heart disease

Pregnancy

Levothyroxine for hypo require 30-50% increase in dose


Hyper: PTU FIRST TRIMESTER, methimazole 2 and 3rd


Uncontrolled thyriud can cause low birth weight, loss, lower IQ, thyroid storm, maternal HTN, neurobehavioral disorders