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12 Cards in this Set
- Front
- Back
Antihistamines |
bind the histamine receptor and prevent binding of histamine 2nd generation are actively pumped out of CNS, less CNS adverse effects (drowsiness) 1st gen: diphenhydramine 2nd gen: loratidine, certizine |
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Bortezomib |
inhibits Nfkb pathway by stabilizing the inhibitor protein Ikb |
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NSAID's |
inhibit COX-1 and COX-2 that leads to decreased prostaglandin synthesis |
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Aspirin (acetylsalicylic acid) |
irreversibly inhibits COX-1 |
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Acetominophen |
analgesic and antipyretic, but not an NSAID Hepatotoxicity with overdose |
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Celecoxib |
only COX-2 selective inhibitor |
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Zileuton |
leukotriene synthesis inhibitor |
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Montelukast |
leukotriene receptor antagonist |
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Omalizumab |
Prevents binding of IgE to Mast cells Used for hard to treat asthma |
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Roflumilast |
inhibits PDE4 and causes accumulation of cAMP anti-inflammatory by preventing activation and recruitment |
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TNF-alpha inhibitors |
Etancercept Infliximab Adalimumab Certolizumab pegol |
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Telcagepant |
CGRP antagonist, used for migraine treatment hepatic toxicity killed development |