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16 Cards in this Set
- Front
- Back
Define this type of hormonal communication:
Intracrine |
Uptake of hormonal precursor and intracellular conversion to effective hormone and subsequent binding to intracellular receptor
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Define this type of hormonal communication:
Intercrine |
Direct transfer of messenger molecule into adjacent cells via gap junctions
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Define this type of hormonal communication:
Autocrine |
Hormone secreted and interacts with receptor on the same cell
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Define this type of hormonal communication:
Paracrine |
Hormone released from cell and interacts with receptor on nearby cells
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Define this type of hormonal communication:
Juxtacrine |
Messenger molecule remains associated with cell membrane of signaling cell and interacts with receptor on adjacent cell
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Define this type of hormonal communication:
Solinocrine |
Messenger molecule secreted into lumen of ductal system (GI, Respiratory, Urogenital)
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Define this type of hormonal communication:
Neurocrine |
Two types
Synaptic - Messneger molecule traverses synaptic space Non-synaptic - Messenger molecule is carried to site of action by ECF or blood |
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Define this type of hormonal communication:
Hemocrine |
Traditional view of hormonal signaling. Cell dumps product into blood to activate distant cells.
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What is a permissive hormonal effect?
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When an initial hormone must prime the target tissue prior to it being receptive to the activating hormone
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What compound acts on the thyotroph cells in the pituitary?
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Thyroid Regulating Hormone
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What compound acts on the thyroid follicles?
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Thyroid Stimulating Hormone
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What inhibits thyroid hormone production?
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Thyroid hormones
Somatostatin Thyroid stimulating hormone |
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What are examples of peptide/polypeptide/protein hormones?
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Insulin
Growth hormone Calcitonin |
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What are examples of lipid derived hormones?
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Steroids (aldosterone, estradiol, cortisol)
Eicosanoids (prostaglandins, thromboxanes) |
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What are some examples of amino acid derived hormones?
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Epinephrine
Norepinephrine Dopamine T3 T4 |
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How are ACTH and melanocyte stimulating hormone (MSH) linked?
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Both are portions of POMC. POMC is cleaved into multiple segments including ACTH and MSH. This is why addison's disease is characterized by an abundance of ACTH and hyperpigmentation
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