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1 Cards in this Set
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Meselson-Stahl experiment
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1. Used to determine that DNA replication is semi-conservative
2. Protocol: (a) Grow E.coli in "heavy" ammonia, and then switch to normal ammonia (b) Harvest aliquots as a function of time, and isolate DNA (c) Separate by DNA density with density gradient centrifugation (3) Showed fractions that correspond to semi-conservative scheme |